Preoperative Acute Normovolaemic Hemodilution (ANH) in combination with Hypotensive Epidural Anaesthesia (HEA) during knee arthroplasty surgery. No effect on transfusion rate. A randomized controlled trial [ISRCTN87597684] [PDF]
BACKGROUND: Hypotensive epidural anaesthesia (HEA) combines a high epidural anaesthesia, performing a sympathetic blockade, with low-dose iv-infusion of epinephrine to stabilize circulation in the conscious patient.
Juelsgaard, Palle +2 more
core +2 more sources
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Measurement of blood flow in the human Achilles tendon in vivo
The purpose of this study was to apply a high-power laser blood flowmeter and laser oxygenation monitor to investigate 1) changes during a single isometric contraction and 2) changes after repeated contractions in blood flow (BF), blood volume (THb), and
Keitaro Kubo +2 more
doaj +1 more source
Regulation of blood flow and volume exchange across the microcirculation
Oxygen delivery to cells is the basic prerequisite of life. Within the human body, an ingenious oxygen delivery system, comprising steps of convection and diffusion from the upper airways via the lungs and the cardiovascular system to the microvascular ...
M. Jacob, D. Chappell, B. F. Becker
semanticscholar +1 more source
Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]
Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah +5 more
core +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Factors Affecting Blood Loss During Thoracoscopic Esophagectomy for Esophageal Carcinoma
Background: Major intraoperative hemorrhage reportedly predicts unfavorable survival outcomes following surgical resection for esophageal carcinoma (EC).
Masayuki Urabe +4 more
doaj +1 more source
Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications [PDF]
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
Bagshaw, S. M. +66 more
core +4 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The effect of bedrest on various parameters of physiological function. part xi- the effect of bedrest on blood volume, urinary volume, and urinary electrolyte excretion [PDF]
Effect of bed rest on blood volume, urinary volume, and urinary electrolyte ...
Cardus, D. +3 more
core +1 more source

