Results 91 to 100 of about 3,202,377 (292)

The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease [PDF]

open access: yes, 2017
Objectives: Exercise is an important part of disease management in patients with non-alcoholic fatty liver disease (NAFLD), but adherence to current exercise recommendations is poor.
Babraj, John A.   +3 more
core   +5 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

THE INFLUENCE OF BLOOD VOLUME AND STORAGE DURATION ON THE ERYTHROCYTE SEDIMENTATION RATE (ESR) VALUE USING THE WESTERGREN METHOD

open access: yesJournal of Vocational Health Studies
Background: Hematological examination is conducted to determine the condition of blood and its components, which are used to establish a diagnosis, support a diagnosis, make a differential diagnosis, monitor disease progression, assess the severity of an
Inna Marlina   +4 more
doaj   +1 more source

Elevated central venous pressure: A consequence of exercise training-induced hypervolemia [PDF]

open access: yes
Resting plasma volumes, and arterial and central venous pressures (CVP) were measured in 16 men before and after exercise training to determine if training-induced hypervolemia could be explained by a change in total vascular capacitance.
Convertino, Victor A.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Determination of Different Biological Factors on the Base of Dried Blood Spot Technology [PDF]

open access: yes, 2011
It is well-known that distinct biological indices (analytes) have distinct variability. We try to use some mathematical algorithms to pick out a set of blood parameters which give an opportunity to retrieve the initial volume of the blood spotted, and ...
Bozhenko, V. K.   +4 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Sprint interval training in the postpartum period maintains the enhanced cardiac output of pregnancy: A case study

open access: yesExperimental Physiology
During pregnancy an increased cardiac output (Q̇) and blood volume (BV) occur to support fetal growth. Increased Q̇ and BV also occur during chronic endurance exercise training and benefit performance.
Normand Richard   +3 more
doaj   +1 more source

Evaluation Model of Microhemodynamics in Finger Skin at Arterial Occlusion and Post-Occlusive Hyperemia

open access: yesFluids
The development of optical noninvasive methods for assessing the functional state of peripheral vessels, including the microcirculatory vascular bed, requires advances in modeling peripheral hemodynamics in order to interpret diagnostic data in terms of ...
Andrey P. Tarasov   +2 more
doaj   +1 more source

BLOOD VOLUME [PDF]

open access: yesAnesthesiology, 1958
W. T. Williams, W. H. Parsons
  +5 more sources

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