Results 41 to 50 of about 2,900,595 (244)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Can the ischemic penumbra be identified on noncontrast CT of acute stroke? [PDF]

open access: yes, 2007
<p><b>Background and Purpose:</b> Early ischemic changes on noncontrast CT in acute stroke include both hypoattenuation and brain swelling, which may have different pathophysiological significance.</p> <p><b>Methods:
Baird, T.   +5 more
core   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

THE CONSTANCY OF THE VOLUME OF THE BLOOD PLASMA [PDF]

open access: yesArchives of Internal Medicine, 1921
INTRODUCTION Until about the middle of the nineteenth century no observations as to the total blood mass in the human body were presented by either clinicians or physiologists. In 1854, Welcker 1 attempted to determine the quantity of blood in the bodies of two criminals by means of a washing out method, and he established as normal the figure of 1/13
openaire   +3 more sources

A venous occlusion plethysmography using a load cell as the sensing element [PDF]

open access: yes, 1990
An application of the load cell as a sensor in venous occlusion plethysmography is presented. In this method the limb volume changes that follow venous occlusion are converted into water volume changes using a water tank for volume change detection.
Oberg, P. Ake   +3 more
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

BLOOD VOLUME IN PERNICIOUS ANEMIA [PDF]

open access: yesArchives of Internal Medicine, 1921
Blood volume in pernicious anemia has been studied but little, and the results obtained have been at considerable variance. Of the literature concerning blood volume, only that portion bearing on pernicious anemia is considered in this paper. Various methods have been followed, such as the dye method of Keith, Rowntree and Geraghty, 1 the carbon ...
openaire   +3 more sources

Blood mobilization from the liver of the anaesthetized dog [PDF]

open access: yes, 1998
The abdominal circulation contains a high proportion of the total blood volume and this can change either passively in response to changes in vascular distending pressure or actively (termed a capacitance response) to changes in sympathetic nervous ...
Drinkhill, M.J.   +3 more
core   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Computer simulation of preflight blood volume reduction as a countermeasure to fluid shifts in space flight [PDF]

open access: yes
Fluid shifts in weightlessness may cause a central volume expansion, activating reflexes to reduce the blood volume. Computer simulation was used to test the hypothesis that preadaptation of the blood volume prior to exposure to weightlessness could ...
Charles, J. B.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy