Results 51 to 60 of about 11,861,111 (294)

The pathophysiology of fluid removal during haemodialysis: implications for blood volume monitoring and determination of dry weight. [PDF]

, 2007
The aim of the research was to characterise the pathophysiology of ultrafiltration (UF) during haemodialysis (HD) using a range of assessment tools. The hypothesis was that objective monitoring would facilitate accurate estimation of dry weight (DW) and ...
Mitra, S., Mitra, Sandip
core  

Impact of cord blood banking technologies on clinical outcome: a Eurocord/Cord Blood Committee (CTIWP), European Society for Blood and Marrow Transplantation and NetCord retrospective analysis [PDF]

, 2016
peer reviewedBACKGROUND Techniques for banking cord blood units (CBUs) as source for hematopoietic stem cell transplantation have been developed over the past 20 years, aimed to improve laboratory efficiency without altering the biologic properties ...
BAUDOUX, Etienne, Kenzey, Chantal, Saccardi, Riccardo, Koegler, Gesine, Freeman, Taryn, Labopin, Myriam, Pouthier, Fabienne, Gluckman, Eliane, Navarrete, Cristina, Ruggeri, Annalisa, Grazzini, Giuliano, Bittencourt, Henrique, Pouthiers, Fabienne, Larghero, Jérome, Tucunduva, Luciana, Ionescu, Irina, Querol, Sergio, Nanni Costa, Alessandro, Lecchi, Lucilla, Regan, Donna, Rocha, Vanderson   +20 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

EFFECT OF MODIFIED ULTRAFILTRATION ON HEMODYNAMICS IN PEDIATRIC CARDIAC SURGERY AT ARMED FORCES INSTITUTE OF CARDIOLOGY/ NATIONAL INSTITUTE OF HEART DISEASES (AFIC/NIHD)

Pakistan Armed Forces Medical Journal, 2020
Objective: To observe the effect of modified ultrafiltration on hemodynamics of pediatric patients. Study Design: A descriptive cross-sectional study. Place and Duration of Study: Pediatric Cardiac Surgery department, AFIC/NIHD Rawalpindi, from Jun
Muneeb Ur Rehman, Tariq Rao, Naila Niaz, Shahid Nafees, Naseem Azad, Muhammad Shoaib Umar   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effects of glycerol and creatine hyperhydration on doping-relevant blood parameters [PDF]

, 2012
Glycerol is prohibited as an ergogenic aid by the World Anti-Doping Agency (WADA) due to the potential for its plasma expansion properties to have masking effects.
Pantazis Takas, Karsten Koehler, Beis, Lukas, Malkova, D., Hambly, Cathertine, Speakman, J.R., Lukas Beis, Easton, Chris, Dalia Malkova, Polyviou, Thelma P., Koehler, Karsten, Pitsiladis, Yannis P., Pitsiladis, Yannis; id_orcid, Beis, L., Hambly, C., Easton, Chris; id_orcid, Polyviou, T.P., Malkova, Dalia, Catherine Hambly, Chris Easton, Thelma P. Polyviou, Yannis P. Pitsiladis, Koehler, K., Pitsiladis, Y.P., Takas, P., Speakman, John R., Hambly, Catherine, Easton, C., Takas, Pantazis, John R. Speakman   +29 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Measurement of blood flow in the human Achilles tendon in vivo

Journal of Physical Fitness and Sports Medicine, 2017
The purpose of this study was to apply a high-power laser blood flowmeter and laser oxygenation monitor to investigate 1) changes during a single isometric contraction and 2) changes after repeated contractions in blood flow (BF), blood volume (THb), and
Keitaro Kubo, Tomonobu Ishigaki, Toshihiro Ikebukuro   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source