Results 41 to 50 of about 11,861,111 (294)

Angiosome-directed endovascular intervention and infrapopliteal disease: Intraoperative evaluation of distal hemodynamic changes and foot blood volume of lower extremity

Frontiers in Surgery, 2022
ObjectivesTo evaluate foot blood volume and hemodynamics and explore whether quantitative techniques can guide revascularization.Materials and methodsA prospective single-center cohort study included thirty-three patients with infrapopliteal artery ...
Chaonan Wang, Junye Chen, Jinsong Lei, Jiang Shao, Zhichao Lai, Kang Li, Wenteng Cao, Xiaolong Liu, Jinghui Yuan, Bao Liu, Bao Liu   +10 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood

, 2010
Here we report the first application of a fractal analysis of the viscoelastic properties of incipient blood clots. We sought to ascertain whether the incipient clot's fractal dimension, Df, could be used as a functional biomarker of hemostasis.
Karl Hawkins, Rhodri Williams, Matthew Lawrence, Lisa Wakeman, Matthew J. Lawrence, Phillip A. Evans, Roger Munro, Adrian Evans, P. Rhodri Williams, Naresh Thirumalai, Roger H. K. Morris   +10 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya. [PDF]

, 2009
BACKGROUND: In sub-Saharan Africa umbilical cord blood may be a useful source of blood for transfusion. Before clinical trials, evidence is needed that cord blood donations, which vary greatly in volume, can be collected and stored into a fixed volume of
Hassall, O, Maitland, Kathryn, Robert Mwakesi, Douglas Denje, Hassall, Oliver, Thitiri, J, Mandaliya, K, Kathryn Maitland, Fegan, Gregory, Denje, Douglas, Bates, I, Bates, Imelda, Imelda Bates, Maitland, K, Oliver Hassall, Bates, Imelda; id_orcid, Wambua, Kongo, Pole, Lewa, Wambua, K, Mandaliya, Kishor, Mwakesi, Robert, Mwakesi, R, Lewa Pole, Fegan, G, Kongo Wambua, Kishor Mandaliya, Denje, D, Thitiri, Johnstone, Johnstone Thitiri, Pole, L, Gregory Fegan, Greg Fegan   +31 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Laboratory analyses for evaluation of platelet disorders and platelet concentrates [PDF]

, 2006
High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core  

Strategies to Overcome Hematocrit and Volume Bias in Dried Blood Spot Analysis

Pharmaceuticals
Background/Objectives: Dried blood spot (DBS) sampling, a technique for collecting capillary blood samples, is widely used in therapeutic drug monitoring, pharmacokinetic and toxicology research, newborn screening, and population health because it ...
Panagiotis-Dimitrios Mingas, Matjaž Cirar, Iztok Grabnar, David Drobne, Tomaž Vovk   +4 more
doaj   +1 more source

A novel method for blood volume estimation using trivalent chromium in rabbit models

Indian Journal of Plastic Surgery, 2014
Background: Blood volume measurement though important in management of critically ill-patients is not routinely estimated in clinical practice owing to labour intensive, intricate and time consuming nature of existing methods.
Prathap Moothamadathil Baby, Pramod Kumar, Rajesh Kumar, Sanu S. Jacob, Dinesh Rawat, V. S. Binu, Kalesh M. Karun   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source