THE EFFECT OF ALTERATIONS IN BLOOD VOLUME ON THE ANEMIA AND HYPOPROTEINEMIA OF HUMAN MALARIA 1 [PDF]
Harry A. Feldman, Franklin D. Murphy
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Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
A STUDY OF THE RENAL CIRCULATION, TUBULAR FUNCTION AND MORPHOLOGY, AND URINARY VOLUME AND COMPOSITION IN DOGS FOLLOWING MERCURY POISONING AND TRANSFUSION OF HUMAN BLOOD 1 [PDF]
Hadley L. Conn+3 more
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Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
The Processes Taking Place in the Body by Which the Number of Erythrocytes Per Unit Volume of Blood is Increased in Acute Experimental Polycythaemia [PDF]
Paul D. Lamson
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Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
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TRAUMATIC SHOCK. X. THE TREATMENT OF HEMORRHAGIC SHOCK IRREVERSIBLE TO REPLACEMENT OF BLOOD VOLUME DEFICIENCY 1 [PDF]
Howard A. Frank+2 more
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The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
On the Origin of the Photoplethysmography Signal: Modeling of Volumetric and Aggregation Effects
This study aimed to examine the mechanisms of the photoplethysmography (PPG) signal formation using Monte Carlo simulations of light transport in biological tissues and experimental observations.
Denis G. Lapitan+3 more
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Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski+13 more
wiley +1 more source