Results 121 to 130 of about 956,209 (253)

Causative agents of bloodstream infections, their susceptibility to antibiotics [PDF]

, 2017
Author of term paper: Eivydas Bučinskis Full title of term paper: Causative agents of bloodstream infections, their susceptibility to antibiotics The aim of this study: To determine the causative agents of bloodstream infections and their susceptibility ...
Bučinskis, Eivydas
core  

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Management and outcome of bloodstream infections: a prospective survey in 121 French hospitals (SPA-BACT survey)

, 2018
Oliver Robineau,1 Jérome Robert,2 Christian Rabaud,3 Jean-Pierre Bedos,4 Emmanuelle Varon,5 Yves Péan,6 Rémy Gauzit,7 Serge Alfandari8 On behalf of the Société de Pathologie Infectieuse de Langue Française (SPILF)
Varon E, Gauzit R, Rabaud C, Robineau O, Bedos JP, Péan Y, Alfandari S, Robert J   +7 more
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Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Intensive care nurses’ knowledge and attitudes towards catheter-related bloodstream infections and evidence-based nursing: results from a descriptive and cross-sectional survey conducted in a hospital in Türkiye

BMC Nursing
Background Intensive care units pose a risk for catheter-related infections because they are the setting of frequent catheter use. This study aimed to determine intensive care nurses’ knowledge and attitudes towards preventing catheter-related ...
Elif Gezginci Akpinar, Habibe Filiz Akdemir, Sonay Goktas   +2 more
doaj   +1 more source

Association between the Antibiotic Factors and the Development of Bacterial Resistance in Bloodstream Infections in the Critical Care Unit

The irrational use of antibiotics is one of the factors in the emergence of Multidrug Resistance (MDR) bacterial infections, which is estimated to continue to increase patient’s mortality until 2050.
Pepy Dwi Endraswari, Atika, Kohar Hari Santoso, David Toffler Ong, Eko Budi Koendhori, Ni Made Mertaniasih   +5 more
core   +1 more source

Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant [PDF]

, 2006
Galactose metabolism is essential for the survival of Trypanosoma brucei, the etiological agent of African sleeping sickness. T. brucei hexose transporters are unable to transport galactose, which is instead obtained through the epimerization of UDP ...
Turnock, Daniel C., Ferguson, Michael A. J., Urbaniak, Michael D.   +2 more
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Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

BMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao, Yujie Luo, Chuanda Zhu, Yanwei Hu   +3 more
wiley   +1 more source