Results 191 to 200 of about 849,075 (295)

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

AXL-SHC1 signaling axis mediates adaptive resistance to HER2-targeted tyrosine kinase inhibitors in HER2-aberrant lung and gastric cancers. [PDF]

NPJ Precis Oncol
Ishida M, Yamada T, Katayama Y, Kawachi H, Sawada R, Nakamura R, Hirai S, Matsui Y, Morimoto K, Onoi K, Nakamura-Sasada A, Horinaka M, Sakai T, Sakakida T, Doi T, Yasumoto K, Goto Y, Furuya N, Taniguchi H, Ogino H, Takayuki N, Chihara Y, Fukuda K, Taniguchi H, Uehara H, Yano S, Tokuda S, Takayama K.   +27 more
europepmc   +1 more source

Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL [PDF]

, 2008
Adrian C. Newland, Aguilar-Santelises, Beckwith, Bosanquet, Breitschopf, Brooks, Chang, Chitambar, Chresta, Ciechanover, Clohessy, Dewson, Dohmen, Fandy, Fecker, Feng-Ting Liu, Hao, Hao, Hideshima, Hongtao Ye, Hsu, Inoue, Jia, Jia, Jia, John G. Gribben, Johnson, Kabore, Kelley, Kluin-Nelemans, Kuroda, Lashinger, Li, Li Jia, Liu, Liu, Lotan, Lundqvist, MacFarlane, McConkey, Ming-Qing Du, Mitsiades, Miyashita, Nikrad, Nishii, Pahler, Perez-Galan, Pigneux, Qin, Rudner, Samir G. Agrawal, Saxena, Sayers, Scheffner, Schmitt, Schwartz, Shah, Smolewski, Strauss, Sutheesophon, Upton, Willis   +61 more
core   +1 more source

Temporally Delayed Deployment of Photo‐Responsive Liquid Crystal Polymer Networks Toward Neural Interfaces

Advanced Healthcare Materials, EarlyView.
Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng, Eleanor Nguyen Jeakle, Mahjabeen Javed, Rajasree Gopala Krishnan, Thomas J. Smith, Yoo Jin Lee, Sahana Dhananjayan, Sasha M. George, Manivannan Sivaperuman Kalairaj, Ali Hasan Zuaiter, Majed O. Althumayri, Hatice Ceylan Koydemir, Joseph J. Pancrazio, Taylor H. Ware   +13 more
wiley   +1 more source

GSK-J4 Suppresses Tumorigenesis by Targeting the PERK-c-Myc Pathway Through Endoplasmic Reticulum Stress Activation in Tuberous Sclerosis Complex. [PDF]

Int J Mol Sci
Lei X, Lang T, Li P, Wu C.
europepmc   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Integrating thermodynamics and molecular kinetics into western blotting teaching

Frontiers in Molecular Biosciences
Zhiyong Wang, Min Wang, Yan Yu, Yanxin Lu, Qiang Xia, Pei Wei   +5 more
doaj   +1 more source

Peritoneal MSCs-derived exosomes suppress CCL24 synthesis through miR-320d delivery contributing to the improvement of peritoneal dialysis-associated fibrosis. [PDF]

Sci Rep
Zhao X, Xi M, Qi H, Xu J, Yuan R, Shi D, Lu J.   +6 more
europepmc   +1 more source

Western Blot [PDF]

, 2019
openaire   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source