Results 81 to 90 of about 166,476 (264)

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

Blow up and quenching for a problem with nonlinear boundary conditions

open access: yesElectronic Journal of Differential Equations, 2015
In this article, we study the blow up behavior of the heat equation $ u_t=u_{xx}$ with $u_x(0,t)=u^{p}(0,t)$, $u_x(a,t)=u^q(a,t)$. We also study the quenching behavior of the nonlinear parabolic equation $v_t=v_{xx}+2v_x^{2}/(1-v)$ with $v_x(0,t)=(1-v(
Nuri Ozalp, Burhan Selcuk
doaj  

Development of safe construction temperature ranges to avoid blow-ups in Ultra-Thin Concrete Pavements

open access: yesMATEC Web of Conferences, 2018
After the construction of an ultra-thin concrete pavement, ambient temperatures may induce an axial force within the pavement due to thermal expansion that can lead to the formation of a blow-up failure.
Mentz Johannes, Hartman Anton
doaj   +1 more source

Blow-Up: The Powers of Scale

open access: yesJoelho, 2017
During the decades following World War II, efforts were made to connect the rhetoric of the human scale with that of a superhuman, geographic or territorial scale.
Ákos Moravánszky
doaj   +1 more source

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

open access: yesAdvanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika   +22 more
wiley   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

open access: yesAdvanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He   +10 more
wiley   +1 more source

Global Existence and Blow-Up of Solutions for a Quasilinear Parabolic Equation with Absorption and Nonlinear Boundary Condition

open access: yesInternational Journal of Analysis and Applications, 2014
This paper deals with the evolution r-Laplacian equation with absorption and nonlinear boundary condition. By using differential inequality techniques, global existence and blow-up criteria of nonnegative solutions are determined.
Iftikhar Ahmed, Chunlai Mu, Pan Zheng
doaj   +2 more sources

Blow-Up Phenomena for Nonlinear Reaction-Diffusion Equations under Nonlinear Boundary Conditions

open access: yesJournal of Function Spaces, 2016
This paper deals with blow-up and global solutions of the following nonlinear reaction-diffusion equations under nonlinear boundary conditions: g(u)t=∇·au∇u+fu  in  Ω×0,T,  ∂u/∂n=bx,u,t  on  ∂Ω×(0,T),  u(x,0)=u0(x)>0,  in  Ω¯, where Ω⊂RN  (N≥2) is a ...
Juntang Ding
doaj   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

open access: yesAdvanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet   +8 more
wiley   +1 more source

Critical exponent and blow-up rate for the omega-diffusion equations on graphs with Dirichlet boundary conditions

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we study the $\omega$-diffusion equation on a graph with Dirichlet boundary conditions $$\displaylines{ u_t(x,t)=\Delta_{\omega}u(x,t)+e^{\beta t}u^{p}(x,t), \quad (x,t)\in S\times(0,\infty), \cr u(x,t)=0, \quad (x,t)\in \partial S ...
Weican Zhou, Miaomiao Chen, Wenjun Liu
doaj  

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