Results 101 to 110 of about 59,222 (260)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Blow‐Up of Solutions for a Coupled Nonlinear Viscoelastic Equation with Degenerate Damping Terms: Without Kirchhoff Term [PDF]

, 2021
Salah Boulaaras, Abdelbaki Choucha, Mohamed Abdalla, Karthikeyan Rajagopal, Sahar Ahmed Idris   +4 more
openalex   +1 more source

Volumetric Additive Manufacturing of Dormant Catalytic Chemistries to Generate Silicone Micro‐ and Millifluidic Devices and Instant Molds

Advanced Science, EarlyView.
We describe use of a novel zero‐dose approach to tomographic volumetric additive manufacturing that has enabled us to print silicone micro‐ and millifluidic devices and instant molds within minutes. The silicones are polymerized using photoactivated dormant platinum photohydrosilylation catalysts that would traditionally be difficult to access in ...
Johanna A. Vandenbrande, Martin P. De Beer, Erika J. Fong, Aftab Bhanvadia, Massimiliano Ferrucci, Wilson Kong, Daniel Wang, Ryan M. Hensleigh, Michell Marufu, James S. Oakdale, Fangyou Xie, Maxim Shusteff, Johanna J. Schwartz   +12 more
wiley   +1 more source

Blow-up analysis for a periodic two-component μ-Hunter-Saxton system. [PDF]

J Inequal Appl, 2018
Guo Y, Xiong T.
europepmc   +1 more source

Osgood type blow-up criterion for the 3D Boussinesq equations with partial viscosity

, 2017
Zhaoyang Shang
openalex   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

On blow-up criteria for a coupled chemotaxis fluid model. [PDF]

J Inequal Appl, 2017
Xie H, Ma C.
europepmc   +1 more source

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source

Nonlinear convection in reaction-diffusion equations under dynamical boundary conditions

Electronic Journal of Differential Equations, 2013
We study the blow-up phenomena for positive solutions of nonlinear reaction-diffusion equations including a nonlinear convection term $partial_t u = Delta u - g(u) cdot abla u + f(u)$ in a bounded domain of $mathbb{R}^N$ under the dissipative ...
Gaelle Pincet Mailly, Jean-Francois Rault   +1 more
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