Results 71 to 80 of about 4,418,049 (248)
, 2012 The Blue Engineer hat sich der Aufgabe widmet, über inner– und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Blue Engineer : Engineers with ecological and social responsibility. Issue 01, summer term 2014
, 2014 The Blue Engineer hat sich der Aufgabe widmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Blue Boar Hotel, Southgate Street, 1965
, 1965 View of the Blue Boar Hotel on Southgate Street still standing in 1965 - quite a bit later than the rest of the properties nearby which were demolished five or more years earlier.
Calow, Dennis;
core
, 2013 The Blue Engineer hat sich der Aufgabe gewidmet, über inner– und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2014 The Blue Engineer hat sich der Aufgabe widmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Differential regulation of sleep by blue, green, and red light in Drosophila melanogaster
Frontiers in Behavioral NeuroscienceIntroductionExposure to blue-enriched light from electronic devices is an emergent disruptor of human sleep, especially at particular times of day. Further dissection of this phenomenon necessitates modeling in a tractable model organism.MethodsThus, we ...
Samuel M. Bond +7 more
doaj +1 more source