Results 61 to 70 of about 4,344,778 (299)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Herein, a series of blue‐emitting Ir(III) phosphors is reported based on the cyclometalating N‐heterocyclic carbenes (NHCs), in which the typical benzimidazolylidene entity is now replaced by a new 7,9‐dihydro‐8H‐purin‐8‐ylidene unit.
Jibiao Jin +9 more
doaj +1 more source
The Blue Engineer hat sich der Aufgabe gewidmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Blue Engineer : Engineers with ecological and social responsibility. Issue 02, summer term 2013
The Blue Engineer hat sich der Aufgabe gewidmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhalgikeit zu ...
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The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The Blue Engineer : Ingenieurinnen und Ingenieure mit sozialer und ökologischer Verantwortung
The Blue Engineer hat sich der Aufgabe widmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
On decompositions of estimators under a general linear model with partial parameter restrictions
A general linear model can be given in certain multiple partitioned forms, and there exist submodels associated with the given full model. In this situation, we can make statistical inferences from the full model and submodels, respectively.
Jiang Bo, Tian Yongge, Zhang Xuan
doaj +1 more source
Colour symbolism plays an important role in everyday life and science. The subject is interdisciplinary and receives significant attention in the literature. It is increasingly entering the field of economics and finance.
Prusak Błażej, Mushafiq Muhammad
doaj +1 more source

