Results 61 to 70 of about 4,418,049 (248)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Two new host materials, 3-(3-(2,12-di-tert-butyl-5,9-dioxa-13b-boranaphtho[3,2,1-de]anthracen-7-yl)phenyl)pyridine (TDBA-Py) and 3,3′-(5-(2,12-di-tert-butyl-5,9-dioxa-13b-boranaphtho[3,2,1-de]anthracen-7-yl)-1,3-phenylene)dipyridine (TDBA-dPy), were ...
Jeongmin Han +6 more
doaj +1 more source
Herein, a series of blue‐emitting Ir(III) phosphors is reported based on the cyclometalating N‐heterocyclic carbenes (NHCs), in which the typical benzimidazolylidene entity is now replaced by a new 7,9‐dihydro‐8H‐purin‐8‐ylidene unit.
Jibiao Jin +9 more
doaj +1 more source
The Blue Engineer hat sich der Aufgabe widmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Blue Engineer : Engineers with ecological and social responsibility. Issue 03, summer term 2013
The Blue Engineer hat sich der Aufgabe gewidmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
On decompositions of estimators under a general linear model with partial parameter restrictions
A general linear model can be given in certain multiple partitioned forms, and there exist submodels associated with the given full model. In this situation, we can make statistical inferences from the full model and submodels, respectively.
Jiang Bo, Tian Yongge, Zhang Xuan
doaj +1 more source
The Blue Engineer hat sich der Aufgabe gewidmet, über inner- und außeruniversitäre Themen mit Bezug zu ganzheitlich verstandener Nachhaltigkeit zu ...
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

