Results 151 to 160 of about 3,387,892 (343)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Heavy metals and metalloid contamination and risk evaluation in the surface sediment of the Bakkhali River estuary in Bangladesh

open access: yesHeliyon
Current state of contamination and subsequent risk of contaminated sediment of a tidal river of Bangladesh was evaluated in the present study. Sediment samples were collected from five locations in the tributary of Bakkhali River estuary during summer ...
Sharmin Jahan   +5 more
doaj   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Strengthening Blue Economy Policy to Achieve Sustainable Fisheries

open access: yesJournal of Sustainable Development and Regulatory Issues (JSDERI)
Particularly in developing nations, the aquaculture and fisheries sector is vital to the nutrition and food security of the global population. Nevertheless, notwithstanding their substantial social and economic potential, fishery resources are ...
Sapriani Sapriani   +2 more
semanticscholar   +1 more source

Exchanging Goods Using Valuable Money

open access: yes, 2016
A group of people wishes to use money to exchange goods efficiently over several time periods. However, there are disadvantages to using any of the goods as money, and in addition fiat money issued in the form of notes or coins will be valueless in the ...
Howard, J. V.
core  

Fiscal multipliers in Ireland using FIR-GEM model. ESRI WP636, September 2019 [PDF]

open access: yes, 2019
This article employs the newly developed FIR-GEM model to compute fiscal multipliers in Ireland for the main tax-spending policy instruments, namely government consumption, public investment, public wages, public transfers, consumption, capital and ...
Varthalitis, Petros
core  

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

How can fisheries’ environmental policies help achieve a sustainable blue economy and blue tourism?

open access: yesDiscover Sustainability
Fishing, fish processing, and tourism are important actors in the blue economy. These industries depend on fishery resources and natural environments.
Yoshihiro Hamaguchi, B. K. Thakur
semanticscholar   +1 more source

Innovations and Labour Market Institutions: An Empirical Analysis of the Italian Case in the middle 90’s. [PDF]

open access: yes
In this paper a dynamic panel data specification is used to assess the relationship between labour market flexibility and innovation activities by distinguishing different technological regimes of activities and geographical areas of the Italian economy.
Fabrizio Pompei, Luca Pieroni
core  

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