Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1 [PDF]
The toxicity of an abnormally long polyglutamine [poly(Q)] tract within specific proteins is the molecular lesion shared by Huntington's disease (HD) and several other hereditary neurodegenerative disorders.
Benzer, Seymour, Kazemi-Esfarjani, Parsa
core +1 more source
Glaucoma and cigarette smoking: a review of narrative reviews [PDF]
Background: Glaucoma is an optic neuropathy associated with visual field changes for which high intra-ocular pressure is a major risk factor. Emerging research indicates that modifiable factors, among which the cigarette smoke, besides IOP may be ...
DI MURRO, FRANCESCA +3 more
core +2 more sources
Distribution of iris color and its association with ocular diseases in a rural population of Iran
Purpose: To determine the distribution of iris color and its relationship with some ocular diseases in a rural population of Iran. Methods: Two rural areas of the north and southwest of Iran were selected by a cross-sectional study using multi-stage ...
Hassan Hashemi +6 more
doaj +1 more source
Background Infectious keratitis, a medical emergency with acute and rapid disease progression may lead to severe visual impairment and even blindness. Herein, an antimicrobial polypeptide from Crassostrea hongkongensis, named URP20, was evaluated for its
Meng Li +6 more
doaj +1 more source
Exploration of the functional consequences of fixational eye movements in the absence of a fovea. [PDF]
A recent theory posits that ocular drifts of fixational eye movements serve to reformat the visual input of natural images, so that the power of the input image is equalized across a range of spatial frequencies.
Agaoglu, Mehmet N, Chung, Susana TL
core
Incidence of postharvest fungal diseases of apples in integrated fruit production
In 2014–2017 an investigation was carried out into the occurrence of fungal storage diseases of five apple varieties (Red Jonaprince, Gala, Golden Delicious, Gloster and Ligol) in the Sandomierz orchard region.
Marek Franciszek Grabowski
doaj +1 more source
Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]
The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A +3 more
core +3 more sources
Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]
The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico +5 more
core +1 more source
A surprising number of humans are equipped with a subpar eye model—featuring pale, colorful irides that are nowhere as good as the original dark ones at guarding the retina from sunlight and do, in fact, raise one’s risk of eye disease.
Paola Bressan
doaj +1 more source
The Effect of Cone Opsin Mutations on Retinal Structure and the Integrity of the Photoreceptor Mosaic [PDF]
Purpose. To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations. Methods. Eleven subjects were recruited, eight of whom have been previously described.
Banin, Eyal +19 more
core +2 more sources

