Results 21 to 30 of about 508,541 (277)

Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1 [PDF]

open access: yes, 2002
The toxicity of an abnormally long polyglutamine [poly(Q)] tract within specific proteins is the molecular lesion shared by Huntington's disease (HD) and several other hereditary neurodegenerative disorders.
Benzer, Seymour, Kazemi-Esfarjani, Parsa
core   +1 more source

Glaucoma and cigarette smoking: a review of narrative reviews [PDF]

open access: yes, 2016
Background: Glaucoma is an optic neuropathy associated with visual field changes for which high intra-ocular pressure is a major risk factor. Emerging research indicates that modifiable factors, among which the cigarette smoke, besides IOP may be ...
DI MURRO, FRANCESCA   +3 more
core   +2 more sources

Distribution of iris color and its association with ocular diseases in a rural population of Iran

open access: yesJournal of Current Ophthalmology, 2019
Purpose: To determine the distribution of iris color and its relationship with some ocular diseases in a rural population of Iran. Methods: Two rural areas of the north and southwest of Iran were selected by a cross-sectional study using multi-stage ...
Hassan Hashemi   +6 more
doaj   +1 more source

The protective effect of URP20 on ocular Staphylococcus aureus and Escherichia coli infection in rats

open access: yesBMC Ophthalmology, 2022
Background Infectious keratitis, a medical emergency with acute and rapid disease progression may lead to severe visual impairment and even blindness. Herein, an antimicrobial polypeptide from Crassostrea hongkongensis, named URP20, was evaluated for its
Meng Li   +6 more
doaj   +1 more source

Exploration of the functional consequences of fixational eye movements in the absence of a fovea. [PDF]

open access: yes, 2020
A recent theory posits that ocular drifts of fixational eye movements serve to reformat the visual input of natural images, so that the power of the input image is equalized across a range of spatial frequencies.
Agaoglu, Mehmet N, Chung, Susana TL
core  

Incidence of postharvest fungal diseases of apples in integrated fruit production

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2021
In 2014–2017 an investigation was carried out into the occurrence of fungal storage diseases of five apple varieties (Red Jonaprince, Gala, Golden Delicious, Gloster and Ligol) in the Sandomierz orchard region.
Marek Franciszek Grabowski
doaj   +1 more source

Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]

open access: yes, 2016
The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A   +3 more
core   +3 more sources

Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]

open access: yes, 2017
The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico   +5 more
core   +1 more source

Why humans evolved blue eyes

open access: yesFrontiers in Psychology
A surprising number of humans are equipped with a subpar eye model—featuring pale, colorful irides that are nowhere as good as the original dark ones at guarding the retina from sunlight and do, in fact, raise one’s risk of eye disease.
Paola Bressan
doaj   +1 more source

The Effect of Cone Opsin Mutations on Retinal Structure and the Integrity of the Photoreceptor Mosaic [PDF]

open access: yes, 2012
Purpose. To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations. Methods. Eleven subjects were recruited, eight of whom have been previously described.
Banin, Eyal   +19 more
core   +2 more sources

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