Results 31 to 40 of about 508,541 (277)

Blue LED light induces dry eye disease via NCOA4-mediated ferritinophagy and iron-overload

Ecotoxicology and Environmental Safety
Purpose: To explore how blue light-emitting diode (LED) exposure affects ferritinophagy and iron homeostasis in the conjunctival epithelium. Methods: C57BL/6 J mice and human conjunctival epithelial cells were exposed to blue LED light.
Qianjie Yang, Qiyuan Li, Yutong Xia, Jiayun Ge, Ying Xie, Chang Shen, Kuangqi Chen, Jinbo Chen, Ye Shen, Jianping Tong, Heding Zhou   +10 more
doaj   +1 more source

Cytochrome b5 protects photoreceptors from light stress-induced lipid peroxidation and retinal degeneration

npj Aging and Mechanisms of Disease, 2017
Neuroscience: Vision is stressful for old flies Paradoxically, light is essential for vision, yet it also induces stress that damages the sensitive cells in the eye. Vikki Weake and her team at Purdue University examined how exposure to blue light causes
Xinping Chen, Hana Hall, Jeffrey P. Simpson, Walter D. Leon-Salas, Donald F. Ready, Vikki M. Weake   +5 more
doaj   +1 more source

Pachychoroid Neovasculopathy Disguising as Age-Related Macular Degeneration Treated by Spironolactone and Anti-VEGF Combination Therapy

Case Reports in Ophthalmology, 2021
Nonresponse of neovascular age-related macular degeneration (nAMD) to anti-vascular endothelial growth factor (anti-VEGF) therapy can often be attributed to misdiagnosis, and pathologies mimicking AMD might require different therapeutic concepts.
Leonie F. Keidel, Benedikt Schworm, Siegfried G. Priglinger, Jakob Siedlecki   +3 more
doaj   +1 more source

Blue-light filtering spectacle lenses for visual performance, sleep, and macular health in adults [PDF]

, 2019
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess whether blue-light filtering spectacle lenses impart effects on visual function, provide protection to the macula, or both.
Busija, L., Downie, L. E., Hull, C., Keller, P. R., Lawrenson, J. G.   +4 more
core   +1 more source

Petal-shaped corneal pattern in a patient with posterior amorphous corneal dystrophy

American Journal of Ophthalmology Case Reports
Purpose: To describe the petal-shaped corneal pattern in a patient with posterior amorphous corneal dystrophy. Observation: A 19-year-old male affected by Graves’ disease presented corneal grey sheet-like opacities and high hyperopia.
Massimiliano Borselli, Costanza Rossi, Adriano Carnevali, Vincenzo Scorcia, Giuseppe Giannaccare   +4 more
doaj   +1 more source

Novel use of trypan blue in ocular surface staining: redefining implications for this vital dye

Revista Brasileira de Oftalmologia, 2011
Different applications of trypan blue (TB) for intraocular surgery have been reported, with very high levels of safety and efficacy. We describe the use of TB as an alternative vital dye for staining the ocular surface to assess the integrity of ...
Renato Ambrósio Jr., Habeeb Ahmad, Diogo Caldas, Ana Laura Caiado Canedo, Bruno Valbon, Frederico Procopio Guerra, Acácio Alves de Souza Lima   +6 more
doaj   +1 more source

The Cone Dysfunction Syndromes [PDF]

, 2016
The cone dysfunction syndromes are a heterogeneous group of inherited, predominantly stationary retinal disorders characterised by reduced central vision, and varying degrees of colour vision abnormalities, nystagmus and photophobia.
Aboshiha, J, Carroll, J, Dubis, AM, Harcastle, AJ, Michaelides, M   +4 more
core  

Involuntary saccades and binocular coordination during visual pursuit in Parkinson's disease [PDF]

, 2016
Prior studies of oculomotor function in Parkinson's disease (PD) have either focused on saccades while smooth pursuit eye movements were not involved, or tested smooth pursuit without considering the effect of any involuntary saccades.
Cao, Bo, Cronin-Golomb, Alice, Dali, Veena, Gagliardi, Celia, Pomplun, Marc, Wu, Chia-Chien, Yazdanbakhsh, Arash   +6 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The effect of blue light exposure in an ocular melanoma animal model

Journal of Experimental & Clinical Cancer Research, 2009
Background Uveal melanoma (UM) cell lines, when exposed to blue light in vitro, show a significant increase in proliferation. In order to determine if similar effects could be seen in vivo, we investigated the effect of blue light exposure in a xenograft
Odashiro Alexandre N, Antecka Emilia, Marshall Jean-Claude, Martins Claudia, Fernandes Bruno F, Maloney Shawn, Di Cesare Sebastian, Dawson William W, Burnier Miguel N   +8 more
doaj   +1 more source