Results 111 to 120 of about 5,683,627 (357)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A cost-consequences and budget impact analysis of blue light-guided cystoscopy with Hexvix in patients diagnosed with non-muscle-invasive bladder cancer in France

, 2023
Jonathan Belsey
openalex   +1 more source

BLUE LIGHT REDUCING SOFTWARE APPLICATIONS FOR MOBILE PHONE SCREENS: MEASUREMENT OF SPECTRAL CHARACTERISTICS AND BIOLOGICAL PARAMETERS [PDF]

, 2020
Sarandis Mitropoulos, V. Tsiantos, A. Americanos, I. Sianoudis, Αικατερίνη Σκουρολιάκου   +4 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Apoptosis induction by different pathways with methylene blue derivative and light from mitochondrial sites in V79 cells [PDF]

, 1998
Barbra B. Noodt, Gry Hege Rodal, Mark Wainwright, Qian Peng, Richard W. Horobin, Jahn M. Nesland, Kristian Berg   +6 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Direct and indirect blue light supplementation on growth, pigments, and gas exchange of young arugula plants

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
It is well-established that the blue (430-460 nm) portion of the visible light spectrum beneficially affects plants, primarily by modulating the relationship between photosynthesis and energy metabolism and promoting chlorophyll accumulation. This study
Paulo H.R. MELO, Edilson COSTA, Giovana P.V. SILVA, Fernanda P.A.P. BORTOLHEIRO, Thaise DANTAS, Flávio F.S. BINOTTI, Eduardo P. VENDRUSCOLO, Gustavo H.C. VIEIRA, Luís H.C. ANDRADE, Sandro M. LIMA   +9 more
doaj   +1 more source

Efficient and Spectrally Stable Blue Perovskite Light‐Emitting Diodes Based on Potassium Passivated Nanocrystals

, 2020
Fei Yang, Hongting Chen, Rui Zhang, Xiaoke Liu, Weizhuo Zhang, Jibin Zhang, Feng Gao, Lei Wang   +7 more
openalex   +2 more sources

Transcriptome Analysis Reveals Differences in Anthocyanin Accumulation in Cotton (Gossypium hirsutum L.) Induced by Red and Blue Light

, 2022
Dongnan Shao, Qian‐Hao Zhu, Qian Liang, Xuefeng Wang, Yanjun Li, Yuqiang Sun, Xinyu Zhang, Feng Liu, Fei Xue, Jie Sun   +9 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source