Results 51 to 60 of about 3,817,359 (296)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in Drosophila

open access: yesnpj Aging and Mechanisms of Disease, 2019
Light is necessary for life, but prolonged exposure to artificial light is a matter of increasing health concern. Humans are exposed to increased amounts of light in the blue spectrum produced by light-emitting diodes (LEDs), which can interfere with ...
Trevor R. Nash   +8 more
doaj   +1 more source

Phototherapy Radiometer with AS7262 Sensor [PDF]

open access: yes, 2019
The phototherapy is a device used in hyperbilirubinemia therapy by using blue light radiation with ranges between 425nm-475nm. The effectiveness of hyperbilirubinemia therapy depends on the amount of energy emitted by light which expressed in μW/cm2. The
Bahtiar, I. S. (Ichwan)   +2 more
core  

Time-resolved photoluminescence of n-doped SrTiO_3

open access: yes, 2008
Following the recent surge of interest in n-doped strontium titanate as a possible blue light emitter, a time-resolved photoluminescence analysis was performed on nominally pure, Nb-doped and oxygen-deficient single-crystal SrTiO3 samples.
di Uccio, U. Scotti   +6 more
core   +1 more source

Light-dependent magnetoreception in birds : increasing intensity of monochromatic light changes the nature of the response [PDF]

open access: yes, 2007
Background The Radical Pair model proposes that magnetoreception is a light-dependent process. Under low monochromatic light from the short-wavelength part of the visual spectrum, migratory birds show orientation in their migratory direction.
Wiltschko, Roswitha   +3 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Effects of blue pulsed light on human physiological functions and subjective evaluation

open access: yesJournal of Physiological Anthropology, 2012
Background It has been assumed that light with a higher irradiance of pulsed blue light has a much greater influence than that of light with a lower irradiance of steady blue light, although they have the same multiplication value of irradiance and ...
Katsuura Tetsuo   +5 more
doaj   +1 more source

3-Wavelength (UV, Blue, Red) Controlled Photo-Confinement for 3D-Printing: Kinetics and Modeling

open access: yesIEEE Access, 2020
Detailed kinetics for a 3-wavelength photopolymerization confinement (PC) system is presented for both numerical solutions and analytic formulas. The dynamic profiles of oxygen, free radicals, and monomer conversion for various situations of: blue-light ...
Jui-Teng Lin   +4 more
doaj   +1 more source

Genome-wide analyses of light-regulated genes in Aspergillus nidulans reveal a complex interplay between different photoreceptors and novel photoreceptor functions.

open access: yesPLoS Genetics, 2021
Fungi sense light of different wavelengths using blue-, green-, and red-light photoreceptors. Blue light sensing requires the "white-collar" proteins with flavin as chromophore, and red light is sensed through phytochrome.
Zhenzhong Yu   +6 more
doaj   +1 more source

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