Results 41 to 50 of about 314,842 (260)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Histological comparison of pancreas and duodenum in Barn Owl, Moorhen and Budgie birds [PDF]

open access: yesTikrit Journal for Agricultural Sciences
The study aimed to describe the histological features of Pancreas and Duodenum in Common Moorhen (Galinula choropus), Barn Owl (Tyto alba) and common Budgie (Melopsittacus undulatus).
Noor Assem Farhan, Ahmed Hussein
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Whitening Efficacy of a Hydroxyapatite Toothpaste and a Blue Covarine Toothpaste: A Comparative In Vitro Study

open access: yesDentistry Journal
Background: There is high demand for white and healthy teeth. Therefore, various whitening toothpastes are commercially available. Hydroxyapatite and blue covarine are two ingredients used in whitening toothpaste formulations.
Joachim Enax   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Effect of Blue Stain on the Toughness of Benguet Pine (Pinus Kesiya Royle Ex. Gordon) Wood

open access: yesJurnal Manajemen Hutan Tropika, 2011
Kualitas kayu pinus Beunguet dipengaruhi oleh banyak faktor, diantaranya serangan blue stain sangat mempengaruhi sifat-sifat kayu seperti keindahan dan ”daya tahan beban tiba-tiba” (toughness) kayu serta mengurangi nilai jual dan pemasaran kayu.
I.G.K. Tapa Darma
doaj  

Platinum blue staining of cells grown in electrospun scaffolds

open access: yesBioTechniques, 2014
Fibroblast cells grown in electrospun polymer scaffolds were stained with platinum blue, a heavy metal stain, and imaged using scanning electron microscopy. Good contrast on the cells was achieved compared with samples that were gold sputter coated.
Mohammed Yusuf   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Do we miss half of the injuries sustained during rape because we cannot see them? An overview of the use of toluidine blue tissue stain in the medical assessment of rape cases

open access: yesSouth African Family Practice, 2018
The prosecution of rape cases is difficult due to the absence of eyewitnesses. McCauley found that the detection of vaginal lacerations increased from one in 24 to 14 in 24 in reported adult rape cases when toluidine blue was used.
J. M. Kotzé, H. Brits
doaj   +1 more source

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