Results 31 to 40 of about 1,266,356 (261)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Alluvial rivers adjust their geometry in response to environmental and anthropogenic disturbances. Flow regulation results in a new geomorphic condition that affects the aquatic ecosystem and its nature.
Chalachew A. Mulatu +3 more
doaj +1 more source
The estimation of evapotranspiration of blue water (ETb) from farmlands, due to irrigation, is crucial to improve water management, especially in regions where water resources are scarce.
Mireia Romaguera +4 more
doaj +1 more source
The wellbeing of millions of Ghanaians hinges on food security. As the country strives to meet the United Nations Sustainable Development Goals Agenda 2030, fish consumption must be sustained.
Berchie Asiedu +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A synergistic framework for dynamic water scarcity assessment: integrated blue and green water
Dynamic assessment of water scarcity utilising blue and green water can enhance water resource management. The traditional water scarcity assessment mainly considers blue water, ignoring green water, for static evaluation.
Jianwei Liu +6 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A General Framework for Setting Quantitative Population Objectives for Wildlife Conservation
https://doi.org/10.15447/sfews.2017v15iss1art8Quantitative population objectives are necessary to successfully achieve conservation goals of secure or robust wildlife populations.
Kristen E. Dybala +9 more
doaj
IntroductionUnderstanding climate change impacts on water footprints (WFs) is crucial for sustainable soybean production.MethodsWe utilized previously calibrated AquaCrop model to assess baseline (1981–2010) and future climate change impacts on soybean ...
Wilfredo Barrera +11 more
doaj +1 more source

