Results 121 to 130 of about 36,167 (307)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The effect of mandala coloring on postpartum blues: a randomized controlled trial

open access: yesBMC Pregnancy and Childbirth
Postpartum blues, also known as postnatal sadness, is a psychological condition often experienced by new mothers, characterized by symptoms such as sadness, excessive crying, irritability, and difficulty making decisions.
Nafiye Dutucu   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

EFFECT OF “BUFAS SMART” EDUCATION ON THE INCIDENCE OF POSTPARTUM BLUES AT RSUD KARTINI KARANGANYAR

open access: yesIndonesian Midwifery and Health Sciences Journal
Background: Postpartum blues, maternity blues or baby blues is a temporary mild mood/affect disorder that occurs on the first day to the 10th day after delivery.
Tri Wikuncoro Tunggal Saputri   +4 more
doaj   +1 more source

Hawaiian blues

open access: yes, 1916
Gift of Dr. Mary Jane Esplen.Piano. [instrumentation]E flat major [key]Modto. [tempo]Ragtime. [form/genre]Beachside; portrait of "The Blues". [illustration]Dulin [engraver]F.J.A. Forster Music Publisher, Chicago.
Walz, Jean [arranger]   +2 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Veneto Blues. A scene and its performative practices [PDF]

open access: yes
openLa musica blues in Italia comincia ad avere una scena importante negli anni '70 del 1900. Analizzando le differenze culturali e stilistiche tra Italia e Stati Uniti d'America si cerca di capire le diversità nella percezione di tale musica e delle ...
PEDIO, FABRIZIO
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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