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Ovine viperin inhibits bluetongue virus replication
Molecular Immunology, 2020Viral infections can lead to interferon production, which achieves its antiviral function primarily by activating the JAK/STAT pathway and inducing multiple interferon-stimulated genes (ISGs). Although considerable ISGs have been identified in antiviral researches, little is known about ISGs in bluetongue virus (BTV) infection.
Di, Kang +8 more
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Bluetongue Virus Assembly and Morphogenesis
2006Like other members of the Reoviridae, bluetongue virus faces the same constraints on structure and assembly that are imposed by a large dsRNA genome. However, since it is arthropod-transmitted, BTV must have assembly pathways that are sufficiently flexible to allow it to replicate in evolutionarily distant hosts.
P, Roy, R, Noad
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Bluetongue virus-induced interferon in cattle
American Journal of Veterinary Research, 1985SUMMARY Calves were inoculated iv with bluetongue virus (btv), serotype 10. Titers of interferon (ifn) in serum and btv in peripheral blood were determined. All inoculated calves produced circulating ifn that persisted for 2 to 4 days. Highest titers of btv in peripheral blood were present after serum ifn was no longer detected.
N J, MacLachlan, J, Thompson
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Bluetongue virus surveillance study
Veterinary Record, 2021Vanessa, Swinson +2 more
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Some morphological features of bluetongue virus
Virology, 1970Abstract Bluetongue (BT) virions have a complex architecture and exist as two principal types: unenveloped “core” particles and more complex membrane-bounded forms. The reovirus-like “core” particles generally have an additional layer of fine surface projections which may, in turn, be covered by a membrane derived from the host cell.
J G, Bowne, A E, Ritchie
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Characterization of bluetongue virus serotype 28
Transboundary and Emerging Diseases, 2019Bluetongue virus (Reoviridae; Orbivirus, BTV), which is usually transmitted by biting midges, affects wild and domestic ruminants worldwide, thereby causing an economically important disease. Recently, a putative new BTV strain was isolated from contaminated vaccine batches.
Velizar Bumbarov +7 more
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Immune Response to Bluetongue Virus Infection
1990Immune responses to bluetongue virus (BTV) have been studied in a variety of animal species with the majority of studies being on the natural ruminant hosts, sheep and cattle. Additional studies have been done on murine species for the purpose of developing monoclonal antibodies and as a potential model system for elucidation of protective immune ...
J L, Stott, B I, Osburn
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Bluetongue virus assembly and exit pathways
2020Bluetongue virus (BTV) is an insect-vectored emerging pathogen of wild ruminants and livestock in many parts of the world. The virion particle is a complex structure of consecutive layers of protein surrounding a genome of 10 double-stranded (ds) RNA segments. BTV has been studied extensively as a model system for large, nonenveloped dsRNA viruses.
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