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Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus [PDF]

Advanced Science
Orbivirus is a genus of double‐stranded RNA viruses that infect a broad spectrum of arthropods and vertebrates. Hemorrhage across different organs is a hallmark pathological feature of orbivirus infection, as exemplified by the bluetongue virus (BTV ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
doaj   +6 more sources

Characterization of a Novel Orbivirus From Cattle Reveals Active Circulation of a Previously Unknown and Pathogenic Orbivirus in Ruminants in Kenya. [PDF]

MSphere, 2023
Arboviruses are among emerging pathogens of public and veterinary health significance. However, in most of sub-Saharan Africa, their role in the aetiologies of diseases in farm animals is poorly described due to paucity of active surveillance and ...
Sandra Junglen, Solomon K Langat, Marietjie Venter   +2 more
exaly   +7 more sources

Tibet Orbivirus, a novel Orbivirus species isolated from Anopheles maculatus mosquitoes in Tibet, China. [PDF]

PLoS ONE, 2014
BACKGROUND: The genus Orbivirus includes a number of important pathogenic viruses, including Bluetongue virus (BTV), African horse sickness virus (AHSV), and Epizootic hemorrhagic disease virus (EHDV).
Minghua Li, Yayun Zheng, Guoyan Zhao, Shihong Fu, David Wang, Zhiyu Wang, Guodong Liang   +6 more
doaj   +6 more sources

Discovery and Characterization of Bukakata Orbivirus (Reoviridae:Orbivirus), a Novel Virus From a Ugandan Bat

Viruses, 2019
While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized.
Amy J Schuh, Anna C Fagre, Luke Nyakarahuka   +2 more
exaly   +4 more sources

A Novel Ephemero- and a New CHeRI Orbivirus Isolated from a Dead Farmed White-Tailed Deer (Odocoileus virginianus) in Florida, USA [PDF]

Viruses
A novel ephemeral fever rhabdovirus and a CHeRI orbivirus of a previously unidentified genetic lineage were isolated in mosquito cell line C6/36 cells as co-infecting agents from the spleen tissue of a dead farmed white-tailed deer (WTD; Odocoileus ...
Emily DeRuyter, Pedro H. O. Viadanna, Kristen Wilson, Zoe White, Amira Richardson, Merrie Urban, Pacharapong Khrongsee, Thais C. S. Rodrigues, Thomas B. Waltzek, Juan M. Campos Krauer, Samantha M. Wisely, Kuttichantran Subramaniam, John A. Lednicky   +12 more
doaj   +3 more sources

Genome and Evolution of Tibet Orbivirus, TIBOV (Genus Orbivirus, Family Reoviridae)

Frontiers in Cellular and Infection Microbiology
Tibet orbivirus (TIBOV) was first isolated from Anopheles maculatus mosquitoes in Xizang, China, in 2009. In recent years, more TIBOV strains have been isolated in several provinces across China, Japan, East Asia, and Nepal, South Asia.
Huanyu Wang, Guodong Liang, Shihong Fu
exaly   +5 more sources

Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved [PDF]

Viruses, 2021
Statin derivatives can inhibit the replication of a range of viruses, including hepatitis C virus (HCV, Hepacivirus), dengue virus (Flavivirus), African swine fever virus (Asfarviridae) and poliovirus (Picornaviridae).
Houssam Attoui, Peter Mertens, Baptiste Monsion   +2 more
exaly   +4 more sources

Yunnan orbivirus, a new orbivirus species isolated from Culex tritaeniorhynchus mosquitoes in China

Journal of General Virology, 2005
An orbivirus designated Yunnan orbivirus (YUOV) was isolated from Culex tritaeniorhynchus mosquitoes collected in the Yunnan province of China. Electron microscopy showed particles with typical orbivirus morphology. The YUOV genome was sequenced completely and compared with previously characterized orbivirus genomes.
Attoui, Houssam, Mohd Jaafar, Fauziah, Belhouchet, Mourad, Aldrovandi, Nicolas, Tao, Sanju, Chen, Boquan, Liang, Guodong, Tesh Robert, B, de Micco, Philippe, de Lamballerie, Xavier   +9 more
core   +9 more sources

Confusions in orbivirus protein classification [PDF]

Virology Journal, 2012
An extensive comparative analysis of orbivirus genomes revealed four cases of unclear numeration and protein designation, due to confused reference to protein size or segment size by which they are encoded. A concise nomenclature based on type species, sequence homology and functional characteristics independent of segment or protein size is suggested.
Dilcher, Meik, Weidmann, Manfred
openaire   +7 more sources

Identification of the First CHeRI Orbivirus 3–5 Strain Isolated from a Dead Farmed White-Tailed Deer (Odocoileus virginianus) Whose Death Had Been Attributed to an Infection by Mule Deerpox Virus [PDF]

Viruses
We report the isolation and coding complete genome sequences of a new CHeRI orbivirus from the spleen of a dead farmed white-tailed deer in Florida whose death was attributed to an infection by mule deerpox virus.
Emily DeRuyter, Pacharapong Khrongsee, Kuttichantran Subramaniam, Kristen Wilson, An-Chi Cheng, Zoe S. White, Amira Richardson, Merrie P. Urban, Juan M. Campos Krauer, Samantha M. Wisely, John A. Lednicky   +10 more
doaj   +2 more sources