Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus [PDF]
Advanced ScienceOrbivirus is a genus of double‐stranded RNA viruses that infect a broad spectrum of arthropods and vertebrates. Hemorrhage across different organs is a hallmark pathological feature of orbivirus infection, as exemplified by the bluetongue virus (BTV ...
Junyong Guan +11 more
doaj +3 more sources
Viruses, 2019 While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized.
Amy J Schuh +2 more
exaly +4 more sources
Orbivirus NS4 Proteins Play Multiple Roles to Dampen Cellular Responses [PDF]
Viruses, 2023 Non-structural protein 4 (NS4) of insect-borne and tick-borne orbiviruses is encoded by genome segment 9, from a secondary open reading frame. Though a protein dispensable for bluetongue virus (BTV) replication, it has been shown to counter the ...
Houssam Attoui +2 more
exaly +4 more sources
A Novel Ephemero- and a New CHeRI Orbivirus Isolated from a Dead Farmed White-Tailed Deer (Odocoileus virginianus) in Florida, USA [PDF]
VirusesA novel ephemeral fever rhabdovirus and a CHeRI orbivirus of a previously unidentified genetic lineage were isolated in mosquito cell line C6/36 cells as co-infecting agents from the spleen tissue of a dead farmed white-tailed deer (WTD; Odocoileus ...
Emily DeRuyter +12 more
doaj +3 more sources
Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved [PDF]
Viruses, 2021 Statin derivatives can inhibit the replication of a range of viruses, including hepatitis C virus (HCV, Hepacivirus), dengue virus (Flavivirus), African swine fever virus (Asfarviridae) and poliovirus (Picornaviridae).
Houssam Attoui +2 more
exaly +4 more sources
Characterization of a Novel Orbivirus from Cattle Reveals Active Circulation of a Previously Unknown and Pathogenic Orbivirus in Ruminants in Kenya [PDF]
MSphere, 2023 Arboviruses are among emerging pathogens of public and veterinary health significance. However, in most of sub-Saharan Africa, their role in the aetiologies of diseases in farm animals is poorly described due to paucity of active surveillance and ...
Sandra Junglen +2 more
exaly +4 more sources
Tibet Orbivirus, a novel Orbivirus species isolated from Anopheles maculatus mosquitoes in Tibet, China. [PDF]
PLoS ONE, 2014 BACKGROUND: The genus Orbivirus includes a number of important pathogenic viruses, including Bluetongue virus (BTV), African horse sickness virus (AHSV), and Epizootic hemorrhagic disease virus (EHDV).
Minghua Li +6 more
doaj +3 more sources
Identification of the First CHeRI Orbivirus 3–5 Strain Isolated from a Dead Farmed White-Tailed Deer (Odocoileus virginianus) Whose Death Had Been Attributed to an Infection by Mule Deerpox Virus [PDF]
VirusesWe report the isolation and coding complete genome sequences of a new CHeRI orbivirus from the spleen of a dead farmed white-tailed deer in Florida whose death was attributed to an infection by mule deerpox virus.
Emily DeRuyter +10 more
doaj +2 more sources
Viruses, 2020 The discovery and characterization of novel arthropod-borne viruses provide valuable information on their genetic diversity, ecology, evolution and potential to threaten animal or public health.
Alexandru Tomazatos +8 more
doaj +2 more sources
Pathogens, 2022 From 1975 to 2021, the United Arab Emirates (UAE) imported more than 1300 live Arabian oryxes (AOs) and scimitar-horned oryxes (SHOs) for conservation programs.
Louis Lignereux +2 more
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