Results 251 to 260 of about 578,151 (361)

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo   +13 more
wiley   +1 more source

Diagnosis, treatment, and management of traumatic diaphragmatic rupture: A multi-center study. [PDF]

open access: yesTurk Gogus Kalp Damar Cerrahisi Derg
Topaloglu O   +9 more
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

open access: yesAdvanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy