Results 31 to 40 of about 39,713 (263)
VaccinesNatural 4-1BBL (CD137L) is a cell membrane-bound protein critical to the expansion, effector function, and survival of CD8+ T cells. We reported the generation of an active soluble oligomeric construct, SA-4-1BBL, with demonstrated immunoprevention and ...
Martin R. Ramos-Gonzalez +7 more
doaj +1 more source
Interference Mitigation for GNSS Receivers Using FFT Excision Filtering Implemented on an FPGA
Eng, 2022 GNSS receivers process signals with very low received power levels (
Tasneem Yousif, Paul Blunt
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Journal of the Egyptian Ophthalmological Society, 2018 Introduction Medial canthus injection as well as subtenon anaesthesia has been used in anterior segment surgery. In this research, we compared the effectiveness and safety of small volume (3 ml) for either technique. Patients and methods Forty eyes of 40
Tamer A Refai, Rehab S Khattab
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Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
The NF-κB signaling network in the life of T cells
Frontiers in ImmunologyNF-κB is a crucial transcription factor in lymphocyte signaling. It is activated by environmental cues that drive lymphocyte differentiation to combat infections and cancer.
Mark A. Daniels +3 more
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Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Aerospace, 2023 The waverider is widely used in hypersonic vehicles with its high aerodynamic performance, but due to the serious aerothermal environment, its sharp leading edge should be blunted.
Zhipeng Qu +5 more
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FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source
Shipin gongye ke-ji, 2023 In this experiment, blunt-snout bream was used as raw material, and the pickled blunt-snout bream was processed by two traditional drying methods, sun-drying and shade-drying, and by measuring peroxide value, acid value, anisidine value, polydilute index,
Fangxue CHEN +10 more
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FEBS Open Bio, EarlyView.This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source