Results 31 to 40 of about 286,241 (363)

Blunt cerebrovascular injury: Our experience and review of current practice

Indian Journal of Vascular and Endovascular Surgery
Background: Blunt cerebrovascular injury (BCVI) is an injury to the carotid or vertebral artery that is nonpenetrating and results from stretching or impingement of the vessel walls due to sudden head movement. Recent studies showed that the incidence of
Ali AlSharqi, Edwin Stephen, Abdulmajeed AlBalushi, Eiman AlAjmi, Hani AlQadhi, Ruqaiya AlShehhi, Ibrahim Abdelhady, Khalifa AlWahaibi   +7 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A Descriptive Study on the Usage of Exploratory Laparotomy for Trauma Patients

Open Access Emergency Medicine, 2020
Ali Pooria,1 Afsoun Pourya,2 Alireza Gheini1 1Department of Cardiology, Lorestan University of Medical Sciences, Khorramabad, Iran; 2Student of Research Committee, Tehran University of Medical Sciences, Tehran, IranCorrespondence: Alireza ...
Pooria A, Pourya A, Gheini A
doaj  

Splenic Injuries at Bugando Medical Centre in Northwestern Tanzania: A Tertiary Hospital Experience. [PDF]

, 2012
Splenic injuries constitute a continuing diagnostic and therapeutic challenge to the trauma or general surgeons practicing in developing countries where sophisticated imaging facilities are either not available or exorbitantly expensive.
Gilyoma Japhet M, Mabula D Mchembe, Giiti, Geofrey, Alphonce B Chandika, Gilyoma, Japhet M, Chandika Alphonce B, Dass Ramesh M, Chalya, Phillipo L, McHembe, Mabula D, Phillipo L Chalya, Chalya Phillipo L, Joseph B Mabula, Dass, Ramesh M, Giiti Geofrey, Mchembe Mabula D, Chandika, Alphonce B, Geofrey Giiti, Ramesh M Dass, Japhet M Gilyoma, Mabula, Joseph B, Mabula Joseph B   +20 more
core   +1 more source

Blunt Splenic Trauma [PDF]

Scandinavian Journal of Surgery, 2006
The treatment of blunt splenic injury has evolved over time from splenectomy in all patients to nonoperative management in stable patients with operation reserved for failures of NOM. While rates of OPSI remain low in trauma patients, splenic salvage in stable patients should be attempted. However, clinical evidence of ongoing blood loss or instability
R M, Forsythe, B G, Harbrecht, A B, Peitzman   +2 more
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Pediatric blunt renal trauma with wide fragments dislocation: successful organ saving management by internal stenting and percutaneous perirenal drain

La Pediatria Medica e Chirurgica, 2014
Children have an high risk of renal damage as a result of blunt trauma. Conservative management is always recommended for lower grades (I to III) but is rather controversial whenever high grade injuries (grade IV and V) are concerned.
C. Olivieri, M.G. Grella, V.D. Catania, A.C. Contini, V. Briganti, A. Calisti   +5 more
doaj   +1 more source

Influence of Non-Uniform Bluntness on Aerodynamic Performance and Aerothermal Characteristics of Waverider

Aerospace, 2023
The waverider is widely used in hypersonic vehicles with its high aerodynamic performance, but due to the serious aerothermal environment, its sharp leading edge should be blunted.
Zhipeng Qu, Wanyu Wang, Houdi Xiao, Yao Xiao, Guangli Li, Kai Cui   +5 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source