Results 151 to 160 of about 141,382 (330)

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Relationship between Calcaneal, Lumbar and Femoral Neck BMD Measured by DXA, and BMI.

, 1998
Keisuke Goto, Naoya Tajima, Etsuo Chosa, Shoichi Kawagoe, Shinichiro Kubo, Koji Totoribe, Hiroshi Kuroki   +6 more
openalex   +2 more sources

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Evaluation of Lumber Lateral Spine FCR Correlated to BMD

, 1998
相澤 一宏, 佐藤 友哉, 三井 衛, 吉井 修, 梅木 克也   +4 more
openalex   +2 more sources

BMD at Multiple Sites and Risk of Fracture of Multiple Types: Long-Term Results From the Study of Osteoporotic Fractures [PDF]

, 2003
Katie L. Stone, Dana G. Seeley, Li‐Yung Lui, Jane A. Cauley, Kristine E. Ensrud, Warren S. Browner, Michael C. Nevitt, Steven R. Cummings   +7 more
openalex   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

P-282 Bone mineral density response to unopposed esterified estrogens; group BMD changes vs individual responses

, 1997
Joseph F. Mortola, Ronald Emkey, Sheryl L. Silfen, J. C. Nolan, John J. Brennan   +4 more
openalex   +1 more source

In Vitro Antihyperglycemic, Antioxidant, and Technofunctional Properties of Fonio Millet Instant Breakfast Meal Enriched With Food By‐Products

Future Postharvest and Food, EarlyView.
ABSTRACT Valorizing agro by‐products and using underutilized food crops are two important ways to guarantee sustained food and health security in the tropics. Hence, this study was to create a functional breakfast meal using a combination of soy cake (SC), cocoa bean shell (CBS), and germinated fonio millet.
Olusola Samuel Jolayemi, Durosimi Yisa, Shukurat Abolore Ismaila, Oluwapelumi Esther Foluso, Modesola Dorcas Boboye   +4 more
wiley   +1 more source

Comparison between os Calcis, Lumbar Vertebrae and Femoral Neck on DEXA in Measuring BMD.

, 1997
Keisuke Goto, Hiroaki Yano, Naoya Tajima, Etsuo Chosa, Shoichi Kawagoe, Norio Sonoda, Takeshi Nonaka   +6 more
openalex   +2 more sources

Impact of Inhaled Corticosteroid (ICS) Therapy on Bone Mineral Density (BMD [PDF]

, 2003
Michael T. Halpern, Jordana K. Schmier, Maria D. Van Kerkhove, Michael L. Watkins, Chris Kalberg   +4 more
openalex   +1 more source