Results 161 to 170 of about 113,813 (285)

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source

Long‐Term Impact of Bariatric Surgery and Dietary Interventions on Weight Loss, Physical Activity, and Food Preferences

Obesity, EarlyView.
ABSTRACT Objective This study aimed to examine changes in dietary intake, physical activity, appetite, and weight following laparoscopic adjustable gastric banding (LAGB), sleeve gastrectomy (SG), Roux‐en‐Y gastric bypass (RYGB), and dietary intervention in adults with severe obesity.
Michael Do, Dana Bliuc, John A. Eisman, Jerry R. Greenfield, Jacqueline R. Center, Malgorzata M. Brzozowska   +5 more
wiley   +1 more source

Vertebral computed tomography attenuation to case-find low bone density in people undergoing lung cancer screening. [PDF]

Br J Radiol
Patel N, Dahl K, O'Rourke R, Williamson A, Lee JC, Fong KM, Yang IA, Marshall HM.   +7 more
europepmc   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Modulation of Arachidonic Acid Metabolism by Pinoresinol Diglucoside Ameliorates Osteogenic Dysfunction via Coordinated NF‐κB Suppression and GSK3β/β‐Catenin Activation in Diabetic Osteoporosis

Phytotherapy Research, EarlyView.
ABSTRACT Diabetic osteoporosis (DOP) is characterized by chronic low‐grade inflammation and impaired bone formation. Pinoresinol diglucoside (PDG), a bioactive compound derived from Eucommia ulmoides Oliv., has shown therapeutic potential in metabolic bone disorders; however, its direct molecular targets and integrated mechanisms remain unclear.
Wenqi Jin, Yujing Tan, Lei Zhang, Weigeng She, Yunhang Chu, Xuenan Chen, Shuai Zhang, Liwei Sun   +7 more
wiley   +1 more source

Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review. [PDF]

Basic Clin Pharmacol Toxicol
Kafa HS, Hauge SC, Hansen D.
europepmc   +1 more source

Safeguarding the Photoluminescence of Silver Sulfide Nanocrystals in Biological Environments via Silica Shielding

Small, EarlyView.
Interactions with biomolecules can alter the photoluminescence of Ag2S nanocrystals, undermining near‐infrared imaging and thermometry. Incorporation into dendritic silica minimizes these interactions and preserves emission intensity, spectral response, and lifetime in plasma and whole blood. This shielding enables more reliable imaging and temperature
Alejandro Hernández Medel, Marina París Ogáyar, Livia Didonè, Peijiang Wang, Ramón Manzorro, Ana B. Hungría, Miriam Granado, Beatriz H. Juárez, Daniel Jaque, Emma Martín Rodríguez, Riccardo Marin, Célia T. Sousa   +11 more
wiley   +1 more source

Raloxifene Versus Continuous Combined Estrogen/Progesterone Therapy: Densitometric and Biochemical Effects in Healthy Postmenopausal Taiwanese Women

, 2009
We treated 116 healthy postmenopausal women (age 47-66 years , mean 57 years) in Taiwan with either raloxifene (RLX) 60 mg (n = 92) or 0.625 mg conjugated equine estrogen plus 5 mg medroxyprogesterone acetate (CCEP, n = 24) daily for 12 months in a ...
TSAI, KEH-SUNG;YEN, MENG-LUH;PAN, HSIEN-AN;WU, MENG-HSING;HSU, SANDY HUEY-JEN;CHENG, WERN-CHERNG;YEN, BETTY LIN-JU, 蔡克嵩;嚴孟祿;潘咸安;吳孟興;徐慧貞;鄭文誠;顏伶汝   +1 more
core  

From Algorithms to Ecosystems: Conceptual Links Between Artificial Intelligence and Biological Control

Systems Research and Behavioral Science, EarlyView.
ABSTRACT The growing convergence between artificial intelligence (AI) and biological sciences has revealed important conceptual parallels between computational systems and ecological processes. This study proposes a systems‐based framework to move beyond purely metaphorical comparisons by distinguishing three analytical levels of correspondence between
João Marcos Rodrigues dos Santos
wiley   +1 more source

The impact of osteoporosis on spinal biomechanical stability in adolescent idiopathic scoliosis: a narrative review of finite element analysis and bone mineral density assessment. [PDF]

Front Bioeng Biotechnol
Hou Z, Wu J, Lu H, Chen C, Han T.
europepmc   +1 more source