Results 81 to 90 of about 113,813 (285)

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Advanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He   +10 more
wiley   +1 more source

Multilevel regression model for TB BMD, FN BMD and LS BMD values when controlling for biological age, height, lean mass and testing for SED and VPA.

, 2014
SE is standard error. Biological age - years from age at peak height velocity (APHV). SED - sedentary time. VPA - vigorous physical activity. Group effect is four different groups according to baseline BMI.Multilevel regression model for TB BMD, FN BMD ...
Katre Maasalu (639158), Jaak Jürimäe (639159), Donvina Vaitkeviciute (639153), Jarek Mäestu (405412), Evelin Lätt (639154), Toivo Jürimäe (639155), Priit Purge (639157), Meeli Saar (639156)   +7 more
core   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Relationship Between Body Composition and Regional BMD in Premenopausal Women with Rheumatoid Arthritis - Original Investigation

, 2009
Aim: This study was performed to investigate the relationship between body composition and regional bone mineral density (BMD) in premenopausal women with rheumatoid arthritis (RA). Material and Methods: 23 RA patients and 31 age and sex-matched healthy
Kazım Şenel, Kadir Yıldırım, Meltem Alkan Melikoğlu, Mustafa Yıldırım, Bedri Seven, Saliha Karatay   +5 more
core  

Effects of antipsychotics on bone mineral density and prolactin levels in patients with schizophrenia: a 12-month prospective study

, 2014
Objective: Effects of conventional and atypical antipsychotics on bone mineral density (BMD) and serum prolactin levels (PRL) were examined in patients with schizophrenia.Methods: One hundred and sixty-three first-episode inpatients with schizophrenia ...
Mi, Guolin, Cao, Bingyu, Tang, Maoqin, Jian, Jia, Hou, Ruihua, Qiu, Huimin, Wang, Mengxin   +6 more
core   +1 more source

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

Advanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing, Lanxin Gu, Lipeng Fu, Xin Gao, Zechuan Li, Hui Zhang, Wenpeng Song, Huixin Lv, Yongsheng Zhou, Ping Zhang   +9 more
wiley   +1 more source

Serum osteocalcin and bone mineral density in postmenopausal women

Universa Medicina, 2016
Since high bone turnover is associated with decreased bone mass, biochemical markers of bone remodeling, such as serum osteocalcin, may be used to assess osteoporosis and to predict fractures in elderly women, particulary those involving trabecular bone,
Lie T. Merijanti Susanto
doaj   +1 more source

Gender-specific associations of appendicular muscle mass with BMD in elderly Italian subjects

, 2014
Currently used diagnostic measures for sarcopenia are based on the evaluation of appendicular skeletal muscle mass (ASMM) divided by height-squared (ASMMI).
Giordano N., Rossi S., Caffarelli C., Cappelli S., Gonnelli S., Nuti R.   +5 more
core   +1 more source

Spatiotemporally Precise Rheumatoid Arthritis Therapy via a Triple‐Locked Cascaded Nanoplatform With Dual‐Channel Self‐Reporting

Advanced Science, EarlyView.
An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu, Wendi Zhu, Shiyun Xu, Shichang Liu, Wenjun Tang, Xiaoyu Ma, Ting Yang, Haojian Yang, Hongtong Wang, Lu Cao, Lijie Tan, Qi Wang   +11 more
wiley   +1 more source

Multilevel regression model for TB BMD, FN BMD and LS BMD controlling for biological age, height, lean body mass and testing for SED and MVPA.

, 2014
SE is standard error. Biological age - years from age at peak height velocity (APHV). SED - sedentary time. MVPA - moderate to vigorous physical activity.
Katre Maasalu (639158), Jaak Jürimäe (639159), Donvina Vaitkeviciute (639153), Jarek Mäestu (405412), Evelin Lätt (639154), Toivo Jürimäe (639155), Priit Purge (639157), Meeli Saar (639156)   +7 more
core   +1 more source