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Bombyx mori UFL1 facilitates BmNPV proliferation by regulating host cell apoptosis through PERK. [PDF]

Archives of Insect Biochemistry and Physiology, Volume 116, Issue 3, July 2024.
Ubiquitin-fold modifier 1 (UFM1) is attached to protein substrates through the sequential activity of an E1 (UBA5)-E2 (UFC1)-E3 (UFL1) cascade. UFL1 is the E3 ligase for UFMylation in vertebrates.
Yijun Zheng, Haonan Meng, Xiaochun Jiang, Shoujun Huang   +3 more
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BmWARS inhibits BmNPV infection via the PI3K-Akt pathway.

Bulletin of Entomological Research
Bombyx mori Tryptophanyl-tRNA synthetase (BmWARS) belongs to the family of Ic-like aminoacyl-tRNA synthetases (aaRSs), whose specific recognition of the substrate Trp, tRNA, maintains the fidelity of protein synthesis.
Jinyang Wang, Xiangrui Ding, Kaifang Jia, Haiyu Chen, Guorong An, Qiaoling Zhao, Dongxu Shen, Zhiyong Qiu, Xuelian Zhang, Heying Qian, Dingguo Xia   +10 more
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Molecular Mechanisms of Bombyx mori Nucleopolyhedrovirus (BmNPV) Entry and Replication in Silkworm Cells: A Review

EAS Journal of Parasitology and Infectious Diseases
Bombyx mori Nucleopolyhedrovirus (BmNPV) is a baculovirus that has been a major threat to the sericulture industry for decades. Through its envelope protein, P64, which interacts with the host receptor, Bombyx mori gp64, BmNPV attaches itself to silkworm
I. I, Ibrahim, Z. Y, Umar, A. N, A. D, Tijjani, U, Abdul, I. H, I. O., Muraina, Y. M, Aniebo, M. C, A. M   +9 more
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Effect of ethanolic plant extractives on cephalic neuroendocrine system of BmNPV inoculated 5th instar larvae of Bombyx mori L. (Lepidoptera, Bombycidae)

ENTOMON
In this research 3000, 5000 and 8000ppm concentration of ethanolic extractives of leaves of Eupatorium odaratum, Hyptis suaveolens and fruits of Aegle marmelos were tested on mulberry silkworm fifth instar larvae of PMxCSR2 inoculated with Bombyx mori ...
Bhaisare Shailesh Shivdas
semanticscholar   +3 more sources

Apolipoprotein D facilitate the proliferation of BmNPV

International Journal of Biological Macromolecules, 2022
The silkworm, Bombyx mori, a model Lepidopteran specie, is an important economic insect. It is specifically infected by Bombyx mori nucleopolyhedrovirus (BmNPV), causing huge losses to the sericulture industry. Therefore, the understandings of the interaction mechanism between BmNPV and the host will help to provide the theoretical basis for the ...
Shigang, Fei, Junming, Xia, Guangyu, Ma, Mengmeng, Zhang, Jingchen, Sun, Min, Feng, Yeyuan, Wang   +6 more
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Single-nucleus sequencing of silkworm larval midgut reveals the immune escape strategy of BmNPV in the midgut during the late stage of infection.

Insect Biochemistry and Molecular Biology, 2023
Junming Xia, Shigang Fei, Yigui Huang, Wenxuan Lai, Yue Yu, Lingying Liang, Hailin Wu, L. Swevers, Jingchen Sun, Min Feng   +9 more
semanticscholar   +2 more sources

Comparative analysis of the intestinal flora of BmNPV-resistant and BmNPV-sensitive silkworm varieties.

Microbial Pathogenesis
Bombyx mori nucleopolyhedrovirus (BmNPV) is a very common and infectious virus that affects silkworms and hinders silk production. To investigate the intestinal flora of BmNPV-resistant and BmNPV-sensitive silkworm varieties, 16 S rDNA high-throughput sequencing was performed.
Xu Yang, Pai Liu, Haodong Yu, Min Ling, Mingzhen Ma, Qiang Wang, Xudong Tang, Zhongyuan Shen, Yiling Zhang   +8 more
semanticscholar   +3 more sources

BmNPV circular RNA-encoded peptide VSP39 promotes viral replication

International Journal of Biological Macromolecules, 2023
CircRNAs are covalently closed single-stranded circular RNA molecules, which are not easily degraded by endonucleases and play vital roles in many biological processes. Currently, most studies on circRNAs focus on endogenous circRNAs in cells, and there are few studies on virus-encoded circRNAs.
Yaxin, Zhang, Xing, Zhang, Zeen, Shen, Qunnan, Qiu, Xinyu, Tong, Jun, Pan, Min, Zhu, Xiaolong, Hu, Chengliang, Gong   +8 more
openaire   +2 more sources

Comprehensive transcriptome sequencing of silkworm Midguts: Uncovering extensive isoform diversity and alternative splicing in BmNPV-Sensitive and BmNPV-resistant strains.

Journal of Invertebrate Pathology
The silkworm, Bombyx mori, stands out as one of the few economically valuable insects within the realm of model organisms. However, Bombyx mori nucleopolyhedrovirus (BmNPV) poses a significant threat, decreasing the quality and quantity of silkworm cocoons.
Min Tang, Yi Liu, Hantao Zhang, Lindan Sun, P. Lü, Keping Chen   +5 more
semanticscholar   +3 more sources

BmNPV Bm60 is a key target gene used by a resistant strain of Bombyx mori to inhibit BmNPV proliferation.

International Journal of Biological Macromolecules
Bombyx mori nucleopolyhedrovirus (BmNPV) is a pathogen that causes significant losses to the silkworm industry. Numerous antiviral genes and proteins have been identified by studying silkworm resistance to BmNPV. However, the molecular mechanism of silkworm resistance to BmNPV is unclear.
Zhigang Hu, Ming-Ya Cao, Yan Zhu, Jie Wang, Yu Lin, Peng Chen, Cheng Lu, Z. Dong, M. Pan   +8 more
semanticscholar   +3 more sources