Results 91 to 100 of about 225,133 (281)

Hypermethylation leads to bone morphogenetic protein 6 downregulation in hepatocellular carcinoma. [PDF]

PLoS ONE, 2014
BACKGROUND: In the liver, bone morphogenetic protein 6 (BMP-6) maintains balanced iron metabolism. However, the mechanism that underlies greater BMP-6 expression in hepatocellular carcinoma (HCC) tissue than adjacent non-cancerous tissue is unclear. This
Yinghua He, Ying Cui, Baiying Xu, Jun Gu, Wei Wang, Xiaoying Luo   +5 more
doaj   +1 more source

Binary-Binary Interactions and the Formation of the PSR B1620-26 Triple System in M4 [PDF]

, 1994
The hierarchical triple system containing the millisecond pulsar PSR B1620-26 in M4 is the first triple star system ever detected in a globular cluster. Such systems should form in globular clusters as a result of dynamical interactions between binaries.
Hut, P., McMillan, S., Rasio, F. A.
core   +2 more sources

Function of BMPs and BMP Antagonists in Adult Bone

Annals of the New York Academy of Sciences, 2006
Abstract:  The expression and function of BMPs and BMPs in bone tissues have been studied for a long time because of their remarkable activities. However, their biological functions in normal bone remodeling in adults were not fully understood until recently. Advanced technologies using gene manipulation were used to study their roles in adulthood. In
openaire   +2 more sources

Immune and Stem Cell‐Mediated Bactericidal Amplification and Bone Remodeling for Infection Clearance and Osteointegration

Advanced Materials, EarlyView.
A pH‐responsive biomaterial interface integrates bactericidal peptides, cell‐recruiting peptides, and magnesium ions into a multifunctional system. Infection‐induced acidification triggers antimicrobial peptide release while cell‐recruiting peptides mobilize bone marrow stem cells.
Zhenyu Li, Siming Zhang, Jiale Dong, Ning Li, Mo Chen, Kunzheng Wang, Bin Li, Guoqing Pan, Jiaxiang Bai, Chen Zhu   +9 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

bantam microRNA is a negative regulator of the Drosophila decapentaplegic pathway

Fly, 2018
Decapentaplegic (Dpp), the Drosophila homolog of the vertebrate bone morphogenetic protein (BMP2/4), is crucial for patterning and growth in many developmental contexts.
Nanci S. Kane, Mehul Vora, Richard W. Padgett, Ying Li   +3 more
doaj   +1 more source

Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/b-tricalcium phosphate porous ceramics [PDF]

, 2009
The association of bone morphogenetic proteins (BMPs) with calcium phosphate bioceramics is known to confer them osteoinductive properties. The aim of this study was to evaluate the surface properties, especially regarding recombinant human BMP-2 (rhBMP-
Alam, Baig, Barroug, Barroug, Benaziz, Bohic, Boix, Charlot, Coradin, Daculsi, Dong, Frolik, Habibovic, Habibovic, Hayakawa, Hughes Wassell, Klenke, Le Nihouannen, Liu, Liu, Matsumoto, Midy, Midy, Murata, Ouizat, Rey, Rey, Rey, Rouahi, Ruppert, Scheufler, Schmoekel, Seeherman, Sumner, Tsujigiwa, Uludag, Vehof, Yuan, Zisch   +38 more
core   +3 more sources

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. [PDF]

, 2019
The type I TGFβ receptor TGFβRI (encoded by Tgfbr1) was ablated in cartilage. The resulting Tgfbr1 Col2 mice exhibited lethal chondrodysplasia. Similar defects were not seen in mice lacking the type II TGFβ receptor or SMADs 2 and 3, the intracellular ...
Baek, Jongseung, Chun, Hyelim, Lopez, Noah, Lyons, Karen M, Razavi, Peyman, Sadik, Joshua Elyahu, Shirazyan, Anna, Wang, Weiguang   +7 more
core  

The effect of BMP-2, BMP-4 and BMP-6 on bone destruction of cholesteatoma presence

American Journal of Otolaryngology, 2013
The aim of our study was to investigate the relationship between the destruction of temporal bone structures, ossicular chain destruction, dissemination of cholesteatoma and the expressions of bone morphogenetic proteins (BMPs), BMP-2, BMP-4 and BMP-6 in patients with acquired cholesteatoma.This study was performed in a total of 80 patients with ...
Öger, Muzaffer, Alpay, Hayrettin Cengiz, Orhan, İsrafil, Önalan Ethem, Ebru, Yanılmaz, Muhammed, Sapmaz, Emrah   +5 more
openaire   +3 more sources