Results 121 to 130 of about 148,190 (307)

Alterations in dynamic regional homogeneity and functional connectivity in lung cancer patients with bone metastasis pain

Brain Research Bulletin
Background: Although previous neuroimaging studies have characterized static brain activity in bone metastasis pain (BMP), its dynamic functional properties remain largely unexplored.
Yu Tang, Tan Cheng, Lin Tang, Xiaoyu Zhou, Jing Zhang, Yong Tan, Hong Yu, Jing Yang, Daihong Liu, Jiuquan Zhang   +9 more
doaj   +1 more source

Local variation in age‐related cortical expansion within and between cross‐sections of distal human long bones

The Anatomical Record, EarlyView.
Abstract Cortical bone expansion is an age‐related process where, through endosteal resorption and periosteal apposition, cross‐sectional diameter increases while cortical thickness decreases in long bone diaphyses. Local variation has been observed in this process between cross‐sectional locations, but few studies have examined directional variation ...
Gregory J. Wehrman, Alice F. Gooding, Adam D. Sylvester, Dawnie W. Steadman, Benjamin M. Auerbach   +4 more
wiley   +1 more source

Isomerization of bis(monoacylglycero)phosphate by acyl migration

Journal of Lipid Research
Bis(monoacylglycero)phosphates (BMPs) are biologically functional acidic lipids present in late endosomes and lysosomes. We recently reported that lysosomal phospholipase A2 (LPLA2, PLA2G15), the lysosomal enzyme mediating BMP catabolism, degrades BMP ...
Akira Abe, Vania Hinkovska-Galcheva, Rakesh Verma, James A. Shayman   +3 more
doaj   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

MicroRNA‐Seq Analysis Reveals a Critical Role for miR‐222 in Bovine Intramuscular Adipogenesis via the DDIT4/mTORC1 Axis

Animal Research and One Health, EarlyView.
Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan, Liang Qiu, Zhenghai Zhou, Zhipeng Zhang, Nanfei Wang, Jiangang Hao, Linsen Zan, Wucai Yang   +7 more
wiley   +1 more source

Dual Effects of β‐TrCP2 Deletion in Bone Homeostasis: Suppression of Osteoclastogenesis and Enhancement of Osteoblast Activity

Arthritis &Rheumatology, Accepted Article.
Objectives To elucidate role of beta‐transducin repeat‐containing protein 2 (β‐TrCP2) in bone homeostasis for its potential as a therapeutic target for osteoporosis. Methods The role of β‐TrCP2 in bone phenotypes was investigated using systemic β‐TrCP1KO and β‐TrCP2KO mice, along with myeloid‐specific conditional β‐TrCP2KO (β‐TrCP2ΔM) mice.
Woo Jung Kim, Sora Han, Hye In Ka, Sun Young Lee, Jiwon Kim, Hyunjeong Joo, Sujung Soh, Gaeun Oh, Kyung Hyun Yoo, Seung Hyun Han, Yeongkag Kwon, Choogon Lee, Kyung‐Hyun Park‐Min, Se Hwan Mun, Young Yang   +14 more
wiley   +1 more source

Treatment‐driven peripheral blood transcriptomic remodelling and baseline predictors of ESSDAI and STAR response to B‐cell therapy in Sjögren's disease

Arthritis &Rheumatology, Accepted Article.
Objective To characterise whole‐blood transcriptomic profiles in adults with active Sjögren's disease (SjD) treated with anti‐CD20 or BlyS/BAFF inhibition, identify markers of clinical response, and define inflammatory pathways linked to non‐response. Methods Whole‐blood RNA sequencing was performed at baseline and week‐24 in participants (n=43) from a
Aimen Ibrahim, Junjie Peng, Eileen Tian, Lucia Martin‐Gutierrez, John Casement, Kyle Thompson, Wan‐Fai Ng, André van Maurik, Elizabeth C Jury, Coziana Ciurtin   +9 more
wiley   +1 more source

Biogas production from Opuntia stricta Haw.: microbial diversity and solid load influence on sludge recycle systems

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The search for alternative and sustainable energy sources becomes urgent as energy demand increases and fossil fuels become less available, especially in water‐scarce regions such as the Brazilian semi‐arid region, where current projections of global warming and the expansion of arid and semi‐arid zones point to a future of desertification ...
Wallysson K. P. Barros, Íthalo B. S. de Abreu, Elias G. M. Silva, João V. P. Tavares, Bruna K. O. Silva, Joyce G. W. Siqueira, Rafael B. de Souza, Rômulo S. C. Menezes, Everardo V. S. B. Sampaio, José Antonio Pérez‐Pimienta, Emmanuel D. Dutra   +10 more
wiley   +1 more source

To BMP or not to BMP - On BMP Signalling during Axis Formation in Mouse Gastruloids

La proteïna morfogenètica òssia 4 (BMP4), secretada pel teixit extraembrionari ectodèrmic, es considera essencial per a la gastrulació i la formació del eix corporal en embrions de ratolí. Tot i això, recentment, models in vitro basats en cèl·lules mare embrionàries de ratolí (mESC) han demostrat que les cèl·lules embrionàries, en absència de teixit ...
openaire   +1 more source