Results 51 to 60 of about 99,722 (229)

Tacrolimus pharmacokinetics in BMT patients [PDF]

Bone Marrow Transplantation, 1998
The pharmacokinetics of tacrolimus following its administration as monotherapy or in combination with corticosteroids or methotrexate to 31 BMT patients are presented. All patients received i.v. tacrolimus initially and were subsequently switched to p.o. dosing. Patients received methotrexate by i.v.
G W, Boswell, I, Bekersky, J, Fay, J, Wingard, J, Antin, D, Weisdorf, R, Maher, W, Fitzsimmons, R, Nash   +8 more
openaire   +2 more sources

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

Arthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry, Bryant R. England, Harlan Sayles, Lindsay N. Helget, Maria Androsenko, Hongsheng Wu, Kaleb Michaud, Bridget Kramer, Jeff A. Newcomb, Mary T. Brophy, Anne Davis‐Karim, Ryan Ferguson, Michael H. Pillinger, Tuhina Neogi, Paul M. Palevsky, James R. O'Dell, Ted R. Mikuls   +16 more
wiley   +1 more source

Early stages of ramified growth in quasi-two-dimensional electrochemical deposition

, 1995
I have measured the early stages of the growth of branched metal aggregates formed by electrochemical deposition in very thin layers. The growth rate of spatial Fourier modes is described qualitatively by the results of a linear stability analysis [D.P ...
D. A. Kessler, D. Grier, D. P. Barkey, D. P. Barkey, E. Ben-Jacob, G. L. M. K. S. Kahanda, J. L. Barton, J. M. Huth, J. R. de Bruyn, J. S. Newman, J.-N. Chazalviel, John R. de Bruyn, K. Linehan, M. D. Pritzker, M. Rosso, R. Aogaki, R. Aogaki, R. Aogaki, T. C. Halsey, T. Viscek, V. Fleury, V. Fleury, W. H. Press, W. W. Mullins, W. W. Mullins, Y. Sawada   +25 more
core   +1 more source

Direct admission to the intensive care unit from the emergency department and mortality in critically ill hematology patients [PDF]

, 2019
Background: The aim of this study was to assess the benefit of direct ICU admission from the emergency department (ED) compared to admission from wards, in patients with hematological malignancies requiring critical care.
Azoulay, Elie, Benoit, Dominique, Bruneel, Fabrice, Chevret, Sylvie, Demoule, Alexandre, Kouatchet, Achille, Lebert, Christine, Lemiale, Virginie, Meert, Anne-Pascale, Mirouse, Adrien, Mokart, Djamel, Nyunga, Martine, Perez, Pierre, Peyrony, Olivier, Pène, Frédéric   +14 more
core   +2 more sources

Donor HLA-specific Abs: to BMT or not to BMT? [PDF]

Bone Marrow Transplantation, 2015
The engraftment failure associated with Abs to donor-specific HLA (DSA) limits options for sensitized BMT candidates. Fourteen of fifteen patients with no other viable donor options were desensitized and transplanted using a regimen of plasmapheresis and low-dose i.v. Ig modified to accommodate pre-BMT conditioning.
M S, Leffell, R J, Jones, D E, Gladstone
openaire   +2 more sources

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

PERSEPSI MASYARAKAT TERHADAP BAITUL MAAL WAT TAMWIL (BMT) DALAM PEMBERDAYAAN EKONOMI MASYARAKAT

al-Uqud: Journal of Islamic Economics, 2018
BMT is a financial institution that is engaged on a micro level, based on  operations on economic principles lawful, fair and profitable. The role of Baitul Tamwil (productive economy) is as Baitul Maal (social roles) that serves to distribute capital ...
Solikhul Hidayat
doaj   +1 more source

Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy. [PDF]

, 2019
Many potentially therapeutic molecules have been identified for treating Duchenne muscular dystrophy. However, targeting those molecules only to sites of active pathology is an obstacle to their clinical use.
Bertoni, Carmen, Flores, Ivan, Ramos, Julian, Tidball, James G, Wang, Ying, Wehling-Henricks, Michelle, Welc, Steven S   +6 more
core  

Laryngoscopic Image Stitching for View Enhancement and Documentation - First Experiences [PDF]

, 2012
One known problem within laryngoscopy is the spatially limited view onto the hypopharynx and the larynx through the endoscope. To examine the complete larynx and hypopharynx, the laryngoscope can be rotated about its main axis, and hence the physician ...
Bergen, Tobias, Friedl, Sven, Muenzenmayer, Christian, Reiter, Maximilian, Schuster, Maria, Wittenberg, Thomas   +5 more
core   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source