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Biochemical and Biophysical Research Communications, 1990
We examined the diuretic-natriuretic activities of rat BNP and human BNP in anesthetized rats in vivo and their vasorelaxant activities for rat thoracic aorta and porcine coronary artery in vitro. Rat BNP was almost equipotent to rat ANP in diuresis and natriuresis with relative potencies of 1.6 and 2.5, respectively, while human BNP exerted no ...
Y, Kambayashi +7 more
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We examined the diuretic-natriuretic activities of rat BNP and human BNP in anesthetized rats in vivo and their vasorelaxant activities for rat thoracic aorta and porcine coronary artery in vitro. Rat BNP was almost equipotent to rat ANP in diuresis and natriuresis with relative potencies of 1.6 and 2.5, respectively, while human BNP exerted no ...
Y, Kambayashi +7 more
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The clearance of BNP modeled using the NT-proBNP–BNP relationship
Biosystems, 2007The ventricular myocardium simultaneously secretes two natriuretic peptides useful in the evaluation of heart failure: BNP, hormonally active, and NT-proBNP, the N-terminal end, non-hormonally active, but ultimately their concentrations differ and their clearance patterns are poorly defined.We measured NT-proBNP and BNP in patients with and without ...
Martin H, Kroll, Pornpen, Srisawasdi
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Radioimmunoassay for brain natriuretic peptide (BNP) detection of BNP in canine brain
Biochemical and Biophysical Research Communications, 1989We established a highly sensitive and specific radioimmunoassay (RIA) for BNP. Our RIA detected BNP-like immunoreactivity (-LI) in the porcine and canine brains but did not detect BNP-LI in the human, monkey or rat brain. The widespread distribution of BNP-LI was demonstrated both in the porcine and canine brains, with the highest concentration in the ...
Hiroshi Itoh +12 more
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The Nurse Practitioner, 2006
ver 5 million Americans have heart failure (HF) and 550,000 new cases are diagnosed each year.' The incidence and increasing prevalence of HF is attributed to the aging population and improved survival from other cardiovascular disorders like coronary artery disease.' Mortality rates for HF are high; 1 in 5 die within 1 year of diagnosis.
Elizabeth, Kinkade, Susan K, Frazier
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ver 5 million Americans have heart failure (HF) and 550,000 new cases are diagnosed each year.' The incidence and increasing prevalence of HF is attributed to the aging population and improved survival from other cardiovascular disorders like coronary artery disease.' Mortality rates for HF are high; 1 in 5 die within 1 year of diagnosis.
Elizabeth, Kinkade, Susan K, Frazier
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BNP and congestive heart failure
Current Problems in Cardiology, 2002Brain natriuretic peptide (BNP), a peptide hormone secreted chiefly by ventricular myocytes, plays a key role in volume homeostasis. The plasma concentration of BNP is raised in various pathological states, especially heart failure. Many studies suggest that measurement of plasma BNP has clinical utility for excluding a diagnosis of heart failure in ...
Martin R, Cowie, Gustavo F, Mendez
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International Journal of Cardiology, 2012
Plasma BNP and NT-proBNP are often used as interchangeable parameters in heart failure care in clinical practice. In our previous study we have shown that inflammation was able to induce increased NT pro BNP in a hospital cohort with chronic heart failure in the elderly, indicating that NT-proBNP/BNP ratio should be evaluated concomitantly with ...
Juliana, Jensen +4 more
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Plasma BNP and NT-proBNP are often used as interchangeable parameters in heart failure care in clinical practice. In our previous study we have shown that inflammation was able to induce increased NT pro BNP in a hospital cohort with chronic heart failure in the elderly, indicating that NT-proBNP/BNP ratio should be evaluated concomitantly with ...
Juliana, Jensen +4 more
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Practical Considerations for BNP Use
Heart Failure Reviews, 2003The evolving paradigm of heart failure has now been expanded to include the favorable neurohormonal, structural and hemodynamic profile of B-type natriuretic peptide [BNP]. As a marker of left ventricular dysfunction, BNP is a practical tool that facilitates diagnosis, contributes to prognostic evaluations and tracks disease severity.
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BNP—Considering a Heartfelt Message
Heart, Lung and Circulation, 2004The natriuretic hormones have been discovered as mediators of the cardiac response to volume overload and mechanical dysfunction. Although there are some physiological differences between atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), it is BNP that has been found to be most useful as a clinical test.
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BNP et NT pro-BNP : performances analytiques et applications cliniques
2017Le BNP (brain natriuretic peptide) et le NT-proBNP (fragment N-terminal du pro-BNP) appartiennent à la famille des peptides natriurétiques de type B. Ils sont synthétisés par les cardiomyocytes de manière équimolaire en réponse à une mise en tension de la paroi du ventricule gauche, dans le but de contrebalancer l’activation du système rénine ...
KHALKI, Hanane +5 more
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