Results 151 to 160 of about 51,741 (305)

SARS-CoV-2 Neutralization with BNT162b2 Vaccine Dose 3

New England Journal of Medicine, 2021
To the Editor: We conducted a global, randomized, placebo-controlled, phase 1–2–3 pivotal trial in which two 30-μg doses of BNT162b2 (Pfizer–BioNTech) were administered 21 days apart (ClinicalTrials.gov number, NCT04368728).
A. Falsey, R. Frenck, E. Walsh, N. Kitchin, J. Absalon, A. Gurtman, S. Lockhart, R. Bailey, K. Swanson, Xia Xu, K. Koury, W. Kalina, David Cooper, Jing Zou, Xuping Xie, Hongjie Xia, Ö. Türeci, E. Lagkadinou, Kristin Tompkins, P. Shi, K. Jansen, U. Şahin, P. Dormitzer, W. Gruber   +23 more
semanticscholar   +1 more source

Optic neuritis secondary to the Pfizer-BioNTech-162b2 COVID-19 vaccine managed with plasmapheresis: A case report and review

Oman Journal of Ophthalmology, 2022
Paras P Shah, Samuel Gelnick, Daniel Zhu, Amanda Wong, Rashmi Verma   +4 more
doaj   +1 more source

Genome‐wide association studies of response and side effects to the BNT162b2 vaccine in Italian healthcare workers: Increased antibody levels and side effects in carriers of the HLA‐A*03:01 allele [PDF]

, 2023
Chiara Magri, Eleonora Marchina, Emanuele Sansone, Pio D’Adamo, Stefania Cappellani, Carlo Bonfanti, Luigina Terlenghi, Giorgio Biasiotto, Isabella Zanella, Emma Sala, Arnaldo Caruso, Massimo Lombardo, Paolo Gasparini, Giuseppe De Palma, Massimo Gennarelli   +14 more
openalex   +1 more source

Comparative analysis of the characteristics and trends of adverse drug reaction reports from patients in Japan and the Japanese Adverse Drug Event Report database

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 515-524, February 2026.
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya, Ryohkan Funakoshi, Koichi Masuyama, Nariyasu Mano, Satoko Hori, Taku Obara   +5 more
wiley   +1 more source

Differences in B-Cell Immunophenotypes and Neutralizing Antibodies Against SARS-CoV-2 After Administration of BNT162b2 (Pfizer-BioNTech) Vaccine in Individuals with and without Prior COVID-19 - A Prospective Cohort Study

Journal of Inflammation Research, 2022
José Javier Morales-Núñez,1 Mariel García-Chagollán,1 José Francisco Muñoz-Valle,1 Saúl Alberto Díaz-Pérez,1 Paola Carolina Torres-Hernández,2 Saraí Citlalic Rodríguez-Reyes,3 Guillermo Santoscoy-Ascencio,4 José Julio Sierra García de Quevedo,4 Jorge ...
Morales-Núñez JJ, García-Chagollán M, Muñoz-Valle JF, Díaz-Pérez SA, Torres-Hernández PC, Rodríguez-Reyes SC, Santoscoy-Ascencio G, Sierra García de Quevedo JJ, Hernández-Bello J   +8 more
doaj  

Impact of timing and combination of different BNT162b2 and ChAdOx1-S COVID-19 basic and booster vaccinations on humoral immunogenicity and reactogenicity in adults

Scientific Reports, 2023
In this single-center observational study with 1,206 participants, we prospectively evaluated SARS-CoV-2-antibodies (anti-S RBD) and vaccine-related adverse drug reactions (ADR) after basic and booster immunization with BNT162b2- and ChAdOx1-S-vaccines ...
Simon Dedroogh, Sven Schmiedl, Petra A. Thürmann, Katharina Graf, Sebastian Appelbaum, Reinhard Koß, Christian Theis, Zewarudin Zia, Jürgen Tebbenjohanns, Serge C. Thal, Michael Dedroogh   +10 more
doaj   +1 more source

Risk of carditis after three doses of vaccination with mRNA (BNT162b2) or inactivated (CoronaVac) covid-19 vaccination: a self-controlled cases series and a case–control study [PDF]

, 2023
Min Fan, Francisco Tsz Tsun Lai, Franco Wing Tak Cheng, Natalie Tsz Ying Tsie, Xue Li, Eric Yuk Fai Wan, Carlos King Ho Wong, Esther W. Chan, Kai Hang Yiu, Ian Chi Kei Wong, Celine Sze Ling Chui   +10 more
openalex   +1 more source

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

Genome-wide association study of BNT162b2 vaccine-related myocarditis identifies potential predisposing functional areas in Hong Kong adolescents [PDF]

Vaccine-related myocarditis associated with the BNT162b2 vaccine is a rare complication, with a higher risk observed in male adolescents. However, the contribution of genetic factors to this condition remains uncertain.
Chan, Sophelia H.S., Chua, Gilbert T., Ip, Patrick, Kwan, Mike Y.W., She, Chun Hing, Tang, Clara S.M., Tsang, Hing Wai, Tsao, Sabrina S.L., Yang, Wanling, Yang, Xingtian   +9 more
core   +1 more source

Impaired Generation of High‐Affinity Memory B Cells and Neutralizing Antibodies Against SARS‐CoV‐2 in Adolescents and Young Adults With Juvenile Idiopathic Arthritis Treated With Tumor Necrosis Factor Inhibitors

ACR Open Rheumatology, Volume 8, Issue 1, January 2026.
Objective We evaluated the immunogenicity of SARS‐CoV‐2 mRNA vaccines in patients with juvenile idiopathic arthritis (JIA), focusing on the generation of spike‐specific memory B cells (MBCs) and of neutralizing antibodies, and assessed the impact of disease‐modifying antirheumatic drugs, particularly tumor necrosis factor inhibitors (TNFi).
Angela Aquilani, Francesca Marinaro, Giusyda Tarantino, Ivan Caiello, Lorenzo Nobili, Eva Piano Mortari, Rebecca Nicolai, Maria Isabella Petrone, Concetta Castilletti, Silvia Magni‐Manzoni, Fabrizio De Benedetti, Rita Carsetti, Emiliano Marasco   +12 more
wiley   +1 more source