Results 121 to 130 of about 5,935,201 (305)

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

The Role Of Gender Diversity In Increasing ESG Performance Through Intellectual Capital

Jurnal Akuntansi
This study examines whether intellectual capital mediates the association between board gender diversity and ESG performance. The samples were selected based on criteria that included all non-financial companies registered on the Indonesia Stock Exchange.
Isnindiah Sofiati, Aria Farah Mita
doaj   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

Advanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu, Jiachen Wang, Chunmeng Ding, Changfa Xia, Yunyong Liu, Yuanjie Zheng, Sheng Chang, Shaokai Zhang, Yutong He, Ruifang Sun, Yunfeng Xi, Yan Liu, Kun Qian, Wanqing Chen   +13 more
wiley   +1 more source

Board gender diversity, financial performance, ESG and audit committee: Capturing ‘glass cliff’ phenomenon in emerging market

Jurnal Akuntansi dan Auditing Indonesia
This study investigates the effect of board gender diversity on financial performance, using ESG performance and audit committee expertise as moderating variables.
Alfa Lailatin Nikmah, Tito IM. Rahman Hakim, Hendra Sanjaya Kusno   +2 more
doaj  

Women on Management Board and Firm Performance: Evidence from The Visegrad Group Countries

Entrepreneurial Business and Economics Review
Objective: The findings of previous research on women serving on company boards have been inconclusive, with some demonstrating a positive influence of women on company performance while others indicate a lack of impact.
Elżbieta Bukalska, Tomasz Sosnowski, Anna Wawryszuk-Misztal   +2 more
doaj   +1 more source

Ownership Structure, Board Composition and Investment Performance [PDF]

In this paper the relation between ownership structure, board composition and firm performance is explored. A panel of Swedish listed firms is used to investigate how board composition affects firm performance.
Palmberg, Johanna, Wiberg, Daniel, Eklund, Johan   +2 more
core  

CEO gender, critical mass of board gender diversity, and ESG performance: UK evidence [PDF]

Purpose This study investigates the relationship between CEO leadership, gender homophily and corporate environmental, social, and governance (ESG) performance.
Zaman, Mahbub, Albitar, Khaldoon, Al-Shaer, Habiba   +2 more
core   +1 more source

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

CEO Power and ESG: The Moderating Role of Gender Diversity in Indonesia

Jurnal Proaksi
Main Purpose - The purpose of this study is to examine how CEO power influences ESG performance, taking into account board gender diversity.  Method -  A total of 82 companies that issued sustainability reports in Indonesia between 2018 and 2022 were ...
Hesniati Hesniati, Madeline Natasha Arifin, Dewi Khornida Marheni, Tony Chandra   +3 more
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source