Results 111 to 120 of about 2,204,937 (293)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

CORPORATE GOVERNANCE AND FIRM PROFITABILITY IN AGRICULTURAL SECTOR: EVIDENCE FROM ASIAN COUNTRIES [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2019
The objective of this research is to determine the relationship between corporate governance practices and firm profitability for the companies in agricultural sector of Asian countries for the period of 2008 to 2017 as agriculture is one of the most ...
Zeshan ANWAR, Bilal AZIZ, Kausar ABBAS
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

PENGARUH OWNERSHIP STRUCTURE, DAN BOARD GOVERNANCE TERHADAP DIVIDEND YIELD (Studi pada Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia Tahun 2012-2016)

open access: yesJurnal Studi Manajemen Organisasi, 2018
This research aims to examine the effect of corporate governance on dividend yield. The ownership structure is devided to instituitional ownership, ownership concentration, managerial ownership  and board governance is divided to board size, board ...
Advento Johanes Pangomo   +1 more
doaj   +1 more source

Collusion in board of directors [PDF]

open access: yes
The aim of this paper is to study what is the best structure of a Board of Directors when collusive aspects between the Board and the CEO are taken into account.
Bourjade, Sylvain, Germain, Laurent
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Board Characteristics and Capital Structure of Malaysia Consumer Products Sector

open access: yesThe International Journal of Banking and Finance, 2018
This study investigated the relationship between board characteristics and capital structure, namely total debt, short-term debt, and long-term debt of firms in the Malaysian consumer products sector for the period 2010 to 2014.
Kuah Yoke Chin, Zuriawati Zakaria
doaj  

Board Characteristics and Bank Stock Performance: Empirical Evidence from the MENA Region

open access: yesRisks
This study examined the relationship between the board characteristics and stock performance of commercial banks. Our analysis is based on a sample of 65 banks across 10 MENA countries and their quantitative data extracted between 2013 and 2022.
Antoine B. Awad   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Corporate Governance and Investment Decisions in Deposit Money Banks in Nigeria [PDF]

open access: yesInternational Journal of Management, Accounting and Economics, 2019
Recently, following financial crises in the global world, the focus of attention has been moved towards how a company is being managed. This study examined the effect of corporate governance on investment decisions of shareholders of listed banks in the ...
Wisdom Okere, Oyebisi Ibidunni
doaj  

Home - About - Disclaimer - Privacy