Results 131 to 140 of about 139,723 (310)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Independence Standards Board - Minutes, Meeting of January 14, 2000: Public Session

open access: yes, 2000
https://egrove.olemiss.edu/aicpa_assoc/1645/thumbnail ...
Independence Standards Board
core  

Development of Busy Board Joyful Media Toward Implementation of the ECE Curriculum to Enhance Childrens' Independence Aged 4-5 Years

open access: yesCakrawala Dini
This research aims to design and develop a busy board joyful media to enhance the independence of children aged 4-5 years. Conducted in two Early Childhood Education (ECE) institutions in Gowa Regency, this study involved 24 children and 4 teachers ...
Ria Nofanti S. Lungka   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Independence Standards Board - Minutes, Telephonic Special meeting of September 23, 1999: Public Session

open access: yes, 1999
https://egrove.olemiss.edu/aicpa_assoc/1642/thumbnail ...
Independence Standards Board
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Who cares about Director Independence?

open access: yes
In this article we have expanded the analysis of the new dataset we created in Santella, Paone, Drago (2005) which analysed and quantified corporate disclosure on directors formally identified as independent by the forty Italian Blue Chips.
Giulia, Paone   +2 more
core  

News release, April 12, 2001: CPA Journal Profile of the Independence Standards Board

open access: yes, 2001
https://egrove.olemiss.edu/aicpa_assoc/1735/thumbnail ...
Independence Standards Board
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Highlights of November 19 ISB Meeting: Independence Standards Board Issues Final Ruling on Mutual Funds

open access: yes, 1999
https://egrove.olemiss.edu/aicpa_assoc/1648/thumbnail ...
Independence Standards Board
core  

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