Results 101 to 110 of about 879,910 (278)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Establishing a core outcome set for creatine transporter deficiency and guanidinoacetate methyltransferase deficiency

Orphanet Journal of Rare Diseases
Background Creatine transporter (CTD) and guanidinoacetate methyltransferase (GAMT) deficiencies are rare inborn errors of creatine metabolism, resulting in cerebral creatine deficiency.
Zahra Nasseri Moghaddam, Emily K. Reinhardt, Audrey Thurm, Beth K. Potter, Maureen Smith, Celeste Graham, Beth H. Tiller, Steven A. Baker, Deborah A. Bilder, Regina Bogar, Jacobus Britz, Rachel Cafferty, Daniel P. Coller, Ton J. DeGrauw, Vicky Hall, Gerald S. Lipshutz, Nicola Longo, Saadet Mercimek-Andrews, Judith S. Miller, Marzia Pasquali, Gajja S. Salomons, Andreas Schulze, Celine P. Wheaton, Kayla F. Williams, Sarah P. Young, Jasmine Li, Sofia Balog, Theresa Selucky, Sylvia Stöckler-Ipsiroglu, Heidi Wallis   +29 more
doaj   +1 more source

A comprehensive dataset of board of directors attributes of Pakistan stock exchange listed non-financial firms. [PDF]

Data Brief, 2022
Khan S, Kamal Y.
europepmc   +1 more source

President's perspective [PDF]

Dallas Fed President Richard W. Fisher explains how members of the Federal Reserve Board of Governors and the Dallas Board of Directors are selected, and their roles in the formulation of Federal Reserve policy.Board of Governors of the Federal Reserve ...
Richard W. Fisher
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Gender Diversity in the Boardroom and Financial Performance of Commercial Banks: Evidence from Bangladesh [PDF]

In today’s corporate world, board diversity is a much talked-about topic and gender diversity is an important aspect of board diversity. Gender diversity refers to the presence of women on corporate boards of directors.
Bose, Sudipta, Dutta, Probal
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

In memoriam Dr. Josep Maria Queraltó, esteemed member of the SEQCML for 35 years

Advances in Laboratory Medicine, 2020
Board of Directors of the Spanish Society of Laboratory Medicine
doaj   +1 more source

REFLECTIONS OF THE EU EXCISES POLICY ON DYNAMICS OF ASSOCIATION OF BIH IN LIGHT OF GLOBAL CHALLENGES

Acta Economica, 2009
Dedication of Bosnia and Herzegovina to European integrations requires a fulfilment of pre-accession obligations that relate to harmonization on excises taxation in BiH with the EU standards.
Динка Антић, PhD
doaj  

Hospital Board of Directors' Composition and Financial Performance: Empirical Evidence from Taiwan. [PDF]

Inquiry, 2021
Chen KC, Hsieh FC, Hsiao YJ.
europepmc   +1 more source