Results 111 to 120 of about 175,994,728 (280)

Hiring Cheerleaders: Board Appointments of "Independent" Directors [PDF]

We provide evidence that firms appoint independent directors who are overly sympathetic to management, while still technically independent according to regulatory definitions.
Andrea Frazzini, Lauren Cohen, Christopher Malloy   +2 more
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Do Women Have a Seat at the Table: Trends in Female Representation Among the Board of Directors in American Urological Association Subspecialty Societies. [PDF]

Cureus, 2022
Dullea AD, Gonzalez DC, Reddy R, Diaz P, Zucker I, Delgado J, Nackeeran S, Blachmann-Braun R, Jones L, Sathe A, Reddy N, Martin L, Syan R, Ramasamy R.   +13 more
europepmc   +1 more source

Minutes of the Board of Directors of Southwestern January 26, 1932

, 1932
January 26, 1932, being the date for the regular annu1 meeting of the Board of Directors, President Chas. E Diehl and Dr. Moore, Secretary, met in the Directors' Room of Palmer Hall.
Southwestern, Board of Directors
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

National Society of Genetic Counselors' Board of Directors response to Myers et al. 'A report of the AGCPD task force to evaluate associations between select admissions requirements, demographics, and performance on ABGC certification examination'. [PDF]

J Genet Couns, 2022
Zierhut H, Jamal L, Riordan S, Wilson P, Carey M, Babu D.   +5 more
europepmc   +1 more source

Health Policy and Systems Research: Where Are We and What Does the Future Hold?

Health Systems & Reform
Health policy and systems research (HPSR) is a relatively young and multidisciplinary field of applied and policy-relevant science. It bridges the worlds of research, practice, and advocacy, and is dedicated to producing evidence to improve health ...
Tolib Mirzoev, Ana B. Amaya, David Daniels, Rumana Huque, Aku Kwamie, Robert Marten, Zubin Cyrus Shroff, Goran Zangana, Kumanan Rasanathan   +8 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Clinical Policy: Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Mild Traumatic Brain Injury: Approved by ACEP Board of Directors, February 1, 2023 Clinical Policy Endorsed by the Emergency Nurses Association (April 5, 2023). [PDF]

Ann Emerg Med, 2023
American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Mild Traumatic Brain Injury, Valente JH, Anderson JD, Paolo WF, Sarmiento K, Tomaszewski CA, Haukoos JS, Diercks DB, Members of the American College of Emergency Physicians Clinical Policies Committee (Oversight Committee), Diercks DB, Anderson JD, Byyny R, Carpenter CR, Friedman B, Gemme SR, Gerardo CJ, Godwin SA, Hahn SA, Hatten BW, Haukoos JS, Kaji A, Kwok H, Lo BM, Mace SE, Moran M, Promes SB, Shah KH, Shih RD, Silvers SM, Slivinski A, Smith MD, Thiessen MEW, Tomaszewski CA, Trent S, Valente JH, Wall SP, Westafer LM, Yu Y, Cantrill SV, Finnell JT, Schulz T, Vandertulip K.   +41 more
europepmc   +1 more source