Results 111 to 120 of about 1,574,881 (361)

Other title: House Bill 2711 - Testimony on Behalf of the Citizens' Utility Ratepayer Board by David Springe, Consumer Counsel

open access: yes, 2008
application/pdf; "February 6, 2008."; Includes a copy of testimony on House Bill 2682 presented before the Kansas Legislature, House Utilities Committee, by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board on January 31, 2008.;
Springe, David.
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Ownership Concentration, Monitoring and Optimal Board Structure [PDF]

open access: yes
The paper analyzes the optimal structure of the board of directors in a firm with a large shareholder sitting on the board. In a one-tier structure the sole board performs all tasks, while in a two-tier structure the management board is in charge of ...
Clara Graziano, Annalisa Luporini
core  

Appraisal of corporate governance in a lower middle income country: The case of Ghana

open access: yesAccounting, 2017
Accountability is instrumental for ensuring that a trusting relationship exists between shareholders and management of corporations in order that there will be enhanced investor confidence.
Seth Oppong   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Corporate Governance, Debt, and Investment Policy during the Great Depression [PDF]

open access: yes
We study a period of severe disequilibrium to investigate whether board characteristics are related to corporate investment, debt usage, and firm value.
John R. Graham   +2 more
core  

Board Size and Firm Performance: The Moderating Role of Female Representation

open access: yesJurnal Akuntansi dan Keuangan
This research aims to investigate the commissioner’s number of boards on the Indonesian go-public company’s performance. The disparity in types of gender begs the question of whether the applicability of women’s governance may lead to firm performance ...
Hendra Wijaya, Gesti Memarista
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy