Results 121 to 130 of about 7,055,998 (308)

Exploring the Cognitive Nature of Boards of Directors and Its Implication for Board Effectiveness [PDF]

open access: yes
In this paper we propose a theoretical framework that emphasizes the development of a shared mental model (SMM) of a board of directors and its impact on board effectiveness and suggest that the accuracy and scope of the SMM in a board will moderate the ...
John E. Prescott   +2 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

BOARD OF DIRECTORS AND THE PRICING OF INITIAL PUBLIC OFFERINGS (IPOS): DOES THE EXISTENCE OF A PROPERLY STRUCTURED BOARD MATTER? EVIDENCE FROM FRANCE [PDF]

open access: yes
The purpose of this study is to introduce the board of directors as a signal of firm quality to abate information asymmetry. This study is based on agency theory and signaling theory to suggest that the existence of properly structured board at the time ...
Anis Mnif
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Board Characteristics, Shariah Supervision, and Corporate Social Responsibility Disclosure in Indonesian Islamic Banks

open access: yesInternational Journal of Islamic Economics and Finance
Corporate social responsibility disclosure in Islamic banking depends not only on governance structures but also on institutional conditions that shape how those structures operate.
Muslichah Muslichah   +2 more
doaj   +1 more source

Columbia Accident Investigation Board Report: Volume 4. Other Technical Documents

open access: yes, 2003
Fourth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations which were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Not size but attributes: the relationship between board attributes and cash holdings

open access: yesCogent Business & Management
This study examines the attributes of board members and the role of board size as a governance factor in determining corporate cash holdings. Our findings indicate that the age and tenure of board members jointly have a positive impact on firms’ cash ...
Kemakorn Chaiprasit   +2 more
doaj   +1 more source

Columbia Accident Investigation Board Report: Volume 5. Other Significant Documents

open access: yes, 2003
Fifth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations that were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

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