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The Borna disease virus (BoDV) 2 nucleoprotein is a conspecific protein that enhances BoDV-1 RNA-dependent RNA polymerase activity

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Cerebrospinal fluid in Borna disease virus 1 (BoDV-1) encephalitis

Journal of the Neurological Sciences, 2023
Borna disease virus 1 (BoDV-1) has been recognized as a rare cause of very severe encephalitis with rapid onset in central Europe. Data on cerebrospinal fluid (CSF) analysis have not yet been analyzed in detail.
Hans Helmut Niller
exaly   +4 more sources

BoDV‐1 infection induces neuroinflammation by activating the TLR4/MyD88/IRF5 signaling pathway, leading to learning and memory impairment in rats

Journal of Medical Virology, 2021
Borna disease virus (BoDV‐1) can infect the hippocampus and limbic lobes of newborn rodents, causing cognitive deficits and abnormal behavior. Studies have found that neuroinflammation caused by viral infection in early life can affect brain development ...

exaly   +4 more sources

Borna Disease Virus 1 (BoDV-1): Aktueller Stand und Perspektiven

Krankenhaushygiene up2date, 2023
Seit wenigen Jahren kann als gesichert gelten, dass Vertreter der Bornaviren in sehr seltenen Fällen vom Tier auf den Menschen übertragen werden können und in der Folge schwere Gehirnentzündungen auslösen.
M. Bauswein   +5 more
semanticscholar   +2 more sources

Bornavirus (BoDV-1) Encephalitis in Children: Update on Diagnosis and Treatment

Neuropediatrics
Infectious encephalitis in children can be caused by several pathogens, very rarely this can be caused by bornaviruses (BoDV-1). Due to the recent discovery of the disease in humans and the small number of cases, especially pediatric infections ...
V. Lieftüchter   +10 more
semanticscholar   +3 more sources

Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts

Neurochemical Research, 2021
Nucleoprotein (P40) is one of the most important proteins of Borna disease virus 1 (BoDV-1), but which proteins it would bind to in the pathogenesis of BoDV-1-infected hosts is unknown. We used lentivirus LV5-P40 overexpressing P40 to infect primary hippocampal neurons and characterized the interactome of P40 with co-immunoprecipitation (Co-IP ...
Yuanxin Li   +14 more
semanticscholar   +3 more sources

Borna Disease (Borna Disease Virus-1, BoDV-1)

2023
Markus Bauswein   +2 more
exaly   +4 more sources

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