Results 1 to 10 of about 192 (126)

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020

Emerging Infectious Diseases, 2021
Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1).
Philip Eisermann, Dennis Rubbenstroth, Daniel Cadar, Corinna Thomé-Bolduan, Petra Eggert, Alexander Schlaphof, Frank Leypoldt, Martin Stangel, Thorsten Fortwängler, Florian Hoffmann, Andreas Osterman, Sabine Zange, Hans-Helmut Niller, Klemens Angstwurm, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Martin Beer, Jonas Schmidt-Chanasit, Dennis Tappe   +19 more
doaj   +1 more source

Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539

Viruses, 2022
Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated.
Liv Bode, Detlef E. Dietrich, Carsten W. Spannhuth, Hanns Ludwig   +3 more
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Ribavirin Inhibits Parrot Bornavirus 4 Replication in Cell Culture. [PDF]

PLoS ONE, 2015
Parrot bornavirus 4 is an etiological agent of proventricular dilatation disease, a fatal neurologic and gastrointestinal disease of psittacines and other birds.
Jeffrey M B Musser, J Jill Heatley, Anastasia V Koinis, Paulette F Suchodolski, Jianhua Guo, Paulina Escandon, Ian R Tizard   +6 more
doaj   +1 more source

Genomic and Micro-Evolutionary Features of Mammalian 2 orthobornavirus (Variegated Squirrel Bornavirus 1, VSBV-1)

Microorganisms, 2021
Mammalian 2 orthobornavirus (VSBV-1) is an emerging zoonotic pathogen discovered in several exotic squirrel species and associated with fatal human encephalitis. The dynamics of VSBV-1 spread and evolution in its presumed natural hosts are unknown. Here,
Dániel Cadar, Jonas Schmidt-Chanasit, Dennis Tappe   +2 more
doaj   +1 more source

Evolutionarily conserved interaction between the phosphoproteins and X proteins of bornaviruses from different vertebrate species. [PDF]

PLoS ONE, 2012
Bornavirus, a non-segmented, negative-strand RNA viruses, is currently classified into several genetically distinct genotypes, such as Borna disease virus (BDV) and avian bornaviruses (ABVs).
Kan Fujino, Masayuki Horie, Tomoyuki Honda, Shoko Nakamura, Yusuke Matsumoto, Ivo M B Francischetti, Keizo Tomonaga   +6 more
doaj   +1 more source

Antiviral treatment perspective against Borna disease virus 1 infection in major depression: a double-blind placebo-controlled randomized clinical trial

BMC Pharmacology and Toxicology, 2020
Background Whether Borna disease virus (BDV-1) is a human pathogen remained controversial until recent encephalitis cases showed BDV-1 infection could even be deadly. This called to mind previous evidence for an infectious contribution of BDV-1 to mental
Detlef E. Dietrich, Liv Bode, Carsten W. Spannhuth, Hartmut Hecker, Hanns Ludwig, Hinderk M. Emrich   +5 more
doaj   +1 more source

Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses

Emerging Microbes and Infections, 2023
Human bornavirus encephalitis is an emerging disease caused by the variegated squirrel bornavirus 1 (VSBV-1) and the Borna disease virus 1 (BoDV-1).
Monika Huhndorf, Julia Juhasz, Mike P. Wattjes, Andreas Schilling, Stefan Schob, Ingmar Kaden, Günter Klaß, Dennis Tappe   +7 more
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Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive–compulsive disorder

BMC Psychiatry, 2022
Background Borna disease virus 1 (BoDV-1) is a non-segmented, negative-strand RNA virus that persistently infects mammals including humans. BoDV-1 worldwide occurring strains display highly conserved genomes with overlapping genetic signatures between ...
Yuanyuan Zhang, A Alwin Prem Anand, Liv Bode, Hanns Ludwig, Hinderk M. Emrich, Detlef E. Dietrich   +5 more
doaj   +1 more source

Canary Bornavirus (Orthobornavirus serini) Infections Are Associated with Clinical Symptoms in Common Canaries (Serinus canaria dom.)

Viruses, 2022
While parrot bornaviruses are accepted as the cause of proventricular dilatation disease (PDD) in psittacine birds, the pathogenic role of bornaviruses in common canaries is still unclear.
Monika Rinder, Noreen Baas, Elisabeth Hagen, Katrin Drasch, Rüdiger Korbel   +4 more
doaj   +1 more source

Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany

Emerging Microbes and Infections, 2022
In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony.
Christina Frank, Jonathan Wickel, Dirk Brämer, Jakob Matschke, Richard Ibe, Caroline Gazivoda, Albrecht Günther, Christian Hartmann, Kordt Rehn, Daniel Cadar, Thomas E. Mayer, Kirsten Pörtner, Hendrik Wilking, Jonas Schmidt-Chanasit, Dennis Tappe   +14 more
doaj   +1 more source