Results 31 to 40 of about 923 (165)

Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein

Acta Crystallographica Section F, Volume 79, Issue 3, Page 51-60, March 2023., 2023
The phosphoprotein is an essential component of the replication complex in bornaviruses. Here, using X‐ray crystallography, the structure of the phosphoprotein from Borna disease virus 1 is presented and its flexibility in solution is characterized.Bornaviruses are RNA viruses with a mammalian, reptilian, and avian host range.
Jack D. Whitehead, Jonathan M. Grimes, Jeremy R. Keown   +2 more
wiley   +1 more source

Bornavirus and the Brain [PDF]

The Journal of Infectious Diseases, 2002
Borna disease virus (BDV) causes central nervous system (CNS) disease that is frequently manifested by behavioral abnormalities. BDV is a nonsegmented, negative, single-stranded RNA virus. On the basis of its unique genetic and biologic features, BDV is the prototypic member of a new virus family, Bornaviridae, within the order Mononegavirales ...
openaire   +2 more sources

Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease

Emerging Microbes and Infections, 2022
Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case definitions, diagnostic algorithms and neuropathology have been described, very little is known about the
Jessica Rauch, Johanna Friederike Steffen, Birgit Muntau, Jana Gisbrecht, Kirsten Pörtner, Christiane Herden, Hans Helmut Niller, Markus Bauswein, Dennis Rubbenstroth, Ute Mehlhoop, Petra Allartz, Dennis Tappe   +11 more
doaj   +1 more source

Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body‐like Pathology in Parrots

Movement Disorders, Volume 37, Issue 12, Page 2345-2354, December 2022., 2022
Abstract Background Several genetic models that recapitulate neurodegenerative features of Parkinson's disease (PD) exist, which have been largely based on genes discovered in monogenic PD families. However, spontaneous genetic mutations have not been linked to the pathological hallmarks of PD in non‐human vertebrates. Objective To describe the genetic
Oswaldo Lorenzo‐Betancor, Livio Galosi, Laura Bonfili, Anna Maria Eleuteri, Valentina Cecarini, Ranieri Verin, Fabrizio Dini, Anna‐Rita Attili, Sara Berardi, Lucia Biagini, Patrizia Robino, Maria Cristina Stella, Dora Yearout, Michael O. Dorschner, Debby W. Tsuang, Giacomo Rossi, Cyrus P. Zabetian   +16 more
wiley   +1 more source

Artificial microRNA guide strand selection from duplexes with no mismatches shows a purine‐rich preference for virus‐ and non‐virus‐based expression vectors in plants

Plant Biotechnology Journal, Volume 20, Issue 6, Page 1069-1084, June 2022., 2022
Summary Artificial microRNA (amiRNA) technology has allowed researchers to direct efficient silencing of specific transcripts using as few as 21 nucleotides (nt). However, not all the artificially designed amiRNA constructs result in selection of the intended ~21‐nt guide strand amiRNA.
Yen‐Wen Kuo, Bryce W. Falk
wiley   +1 more source

Bornavirus Antigens in Psittaciformes Infected with Psittaciform Bornavirus and their Use in Diagnostic Procedures

Archives of Veterinary Science and Medicine, 2020
This study describes the occurrence of psittaciform bornavirus antigens and antibodies in tissues of birds persistently infected with psittaciform bornavirus. Analysis of serum of infected birds shows that antibodies against the P40 nucleoprotein occur most commonly, whereas antibodies to the glycoprotein are virtually completely absent.
Josephine M McHugh, Siwo R de Kloet
openaire   +1 more source

Investigation of astrovirus and bornavirus in the cerebrospinal fluid of dogs clinically diagnosed with meningoencephalitis of unknown etiology

Journal of Veterinary Internal Medicine, 2020
Background Non‐suppurative encephalitides in a variety of species, including humans and dogs, have been linked to infection by astroviruses and bornaviruses.
Audrey Collinet, Gabriel Garcia, Jim Wellehan, April Childress, Sheila Carrera‐Justiz   +4 more
doaj   +1 more source

Serological Surveillance and Risk Factor Analysis for Parrot Bornavirus in Taiwan. [PDF]

Transbound Emerg Dis
Parrots are traded globally and pose a substantial risk for disease transmission involving parrot‐specific pathogens. Parrot bornavirus (PaBV) belongs to the Bornaviridae family and encompasses two clades: alphapsittaciforme (PaBV‐1 to ‐4, PaBV‐7, and ‐8) and betapsittaciforme (PaBV‐5 and PaBV‐6). These clades cause proventricular dilatation disease, a
Chen JY, Wu MC, Fang ZS, Chen HW.
europepmc   +2 more sources

Aquatic Bird Bornavirus 1 in Wild Geese, Denmark

Emerging Infectious Diseases, 2015
To investigate aquatic bird bornavirus 1 in Europe, we examined 333 brains from hunter-killed geese in Denmark in 2014. Seven samples were positive by reverse transcription PCR and were 98.2%–99.8% identical; they were also 97.4%–98.1% identical to ...
Anders F. Thomsen, Jesper B. Nielsen, Charlotte K. Hjulsager, Mariann Chriél, Dale A. Smith, Mads F. Bertelsen   +5 more
doaj   +1 more source

Phylogenetic Analysis Supports Horizontal Transmission as a Driving Force of the Spread of Avian Bornaviruses.

PLoS ONE, 2016
BackgroundAvian bornaviruses are a genetically diverse group of viruses initially discovered in 2008. They are known to infect several avian orders.
Dennis Rubbenstroth, Volker Schmidt, Monika Rinder, Marko Legler, Sönke Twietmeyer, Phillip Schwemmer, Victor M Corman   +6 more
doaj   +1 more source