Results 21 to 30 of about 192 (126)
Vertical Transmission of Avian Bornavirus in Psittacines
To the Editor: Proventricular dilatation disease (PDD) is a fatal disease in psittacines that jeopardizes critical species conservation projects, such as that involving the Spix’s macaw (Cyanopsitta spixii), the world’s most endangered bird species (1).
Michael Lierz +5 more
doaj +3 more sources
Viral infections in critical care: a narrative review
Summary Viral infections form a substantial part of the intensive care workload, even before the recent and ongoing COVID‐19 pandemic. The growing availability of molecular diagnostics for viral infections has led to increased recognition of these pathogens. This additional information, however, provides new challenges for interpretation and management.
A. Conway Morris, A. Smielewska
wiley +1 more source
Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein
The phosphoprotein is an essential component of the replication complex in bornaviruses. Here, using X‐ray crystallography, the structure of the phosphoprotein from Borna disease virus 1 is presented and its flexibility in solution is characterized.Bornaviruses are RNA viruses with a mammalian, reptilian, and avian host range.
Jack D. Whitehead +2 more
wiley +1 more source
Clinical Features of BoDV-1 Encephalitis: A Systematic Review
Human cases of fatal encephalitis caused by Borna disease virus 1 (BoDV-1) have been increasingly reported. We envisaged the present systematic review in order to provide a comprehensive summary of clinical features associated with BoDV-1 encephalitis ...
Matteo Riccò +3 more
doaj +1 more source
Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body‐like Pathology in Parrots
Abstract Background Several genetic models that recapitulate neurodegenerative features of Parkinson's disease (PD) exist, which have been largely based on genes discovered in monogenic PD families. However, spontaneous genetic mutations have not been linked to the pathological hallmarks of PD in non‐human vertebrates. Objective To describe the genetic
Oswaldo Lorenzo‐Betancor +16 more
wiley +1 more source
Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case definitions, diagnostic algorithms and neuropathology have been described, very little is known about the
Jessica Rauch +11 more
doaj +1 more source
Bornavirus and the Brain [PDF]
Borna disease virus (BDV) causes central nervous system (CNS) disease that is frequently manifested by behavioral abnormalities. BDV is a nonsegmented, negative, single-stranded RNA virus. On the basis of its unique genetic and biologic features, BDV is the prototypic member of a new virus family, Bornaviridae, within the order Mononegavirales ...
openaire +2 more sources
Summary Artificial microRNA (amiRNA) technology has allowed researchers to direct efficient silencing of specific transcripts using as few as 21 nucleotides (nt). However, not all the artificially designed amiRNA constructs result in selection of the intended ~21‐nt guide strand amiRNA.
Yen‐Wen Kuo, Bryce W. Falk
wiley +1 more source
New World camelids are sentinels for the presence of Borna disease virus
Abstract Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV‐1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white‐toothed shrew (Crocidura leucodon) was identified as a persistently infected species involved in virus transmission.
Alexandra J. Malbon +12 more
wiley +1 more source
This study describes the occurrence of psittaciform bornavirus antigens and antibodies in tissues of birds persistently infected with psittaciform bornavirus. Analysis of serum of infected birds shows that antibodies against the P40 nucleoprotein occur most commonly, whereas antibodies to the glycoprotein are virtually completely absent.
Josephine M McHugh, Siwo R de Kloet
openaire +1 more source

