Results 21 to 30 of about 192 (126)

Vertical Transmission of Avian Bornavirus in Psittacines

open access: yesEmerging Infectious Diseases, 2011
To the Editor: Proventricular dilatation disease (PDD) is a fatal disease in psittacines that jeopardizes critical species conservation projects, such as that involving the Spix’s macaw (Cyanopsitta spixii), the world’s most endangered bird species (1).
Michael Lierz   +5 more
doaj   +3 more sources

Viral infections in critical care: a narrative review

open access: yesAnaesthesia, Volume 78, Issue 5, Page 626-635, May 2023., 2023
Summary Viral infections form a substantial part of the intensive care workload, even before the recent and ongoing COVID‐19 pandemic. The growing availability of molecular diagnostics for viral infections has led to increased recognition of these pathogens. This additional information, however, provides new challenges for interpretation and management.
A. Conway Morris, A. Smielewska
wiley   +1 more source

Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein

open access: yesActa Crystallographica Section F, Volume 79, Issue 3, Page 51-60, March 2023., 2023
The phosphoprotein is an essential component of the replication complex in bornaviruses. Here, using X‐ray crystallography, the structure of the phosphoprotein from Borna disease virus 1 is presented and its flexibility in solution is characterized.Bornaviruses are RNA viruses with a mammalian, reptilian, and avian host range.
Jack D. Whitehead   +2 more
wiley   +1 more source

Clinical Features of BoDV-1 Encephalitis: A Systematic Review

open access: yesZoonotic Diseases, 2023
Human cases of fatal encephalitis caused by Borna disease virus 1 (BoDV-1) have been increasingly reported. We envisaged the present systematic review in order to provide a comprehensive summary of clinical features associated with BoDV-1 encephalitis ...
Matteo Riccò   +3 more
doaj   +1 more source

Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body‐like Pathology in Parrots

open access: yesMovement Disorders, Volume 37, Issue 12, Page 2345-2354, December 2022., 2022
Abstract Background Several genetic models that recapitulate neurodegenerative features of Parkinson's disease (PD) exist, which have been largely based on genes discovered in monogenic PD families. However, spontaneous genetic mutations have not been linked to the pathological hallmarks of PD in non‐human vertebrates. Objective To describe the genetic
Oswaldo Lorenzo‐Betancor   +16 more
wiley   +1 more source

Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease

open access: yesEmerging Microbes and Infections, 2022
Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case definitions, diagnostic algorithms and neuropathology have been described, very little is known about the
Jessica Rauch   +11 more
doaj   +1 more source

Bornavirus and the Brain [PDF]

open access: yesThe Journal of Infectious Diseases, 2002
Borna disease virus (BDV) causes central nervous system (CNS) disease that is frequently manifested by behavioral abnormalities. BDV is a nonsegmented, negative, single-stranded RNA virus. On the basis of its unique genetic and biologic features, BDV is the prototypic member of a new virus family, Bornaviridae, within the order Mononegavirales ...
openaire   +2 more sources

Artificial microRNA guide strand selection from duplexes with no mismatches shows a purine‐rich preference for virus‐ and non‐virus‐based expression vectors in plants

open access: yesPlant Biotechnology Journal, Volume 20, Issue 6, Page 1069-1084, June 2022., 2022
Summary Artificial microRNA (amiRNA) technology has allowed researchers to direct efficient silencing of specific transcripts using as few as 21 nucleotides (nt). However, not all the artificially designed amiRNA constructs result in selection of the intended ~21‐nt guide strand amiRNA.
Yen‐Wen Kuo, Bryce W. Falk
wiley   +1 more source

New World camelids are sentinels for the presence of Borna disease virus

open access: yesTransboundary and Emerging Diseases, Volume 69, Issue 2, Page 451-464, March 2022., 2022
Abstract Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV‐1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white‐toothed shrew (Crocidura leucodon) was identified as a persistently infected species involved in virus transmission.
Alexandra J. Malbon   +12 more
wiley   +1 more source

Bornavirus Antigens in Psittaciformes Infected with Psittaciform Bornavirus and their Use in Diagnostic Procedures

open access: yesArchives of Veterinary Science and Medicine, 2020
This study describes the occurrence of psittaciform bornavirus antigens and antibodies in tissues of birds persistently infected with psittaciform bornavirus. Analysis of serum of infected birds shows that antibodies against the P40 nucleoprotein occur most commonly, whereas antibodies to the glycoprotein are virtually completely absent.
Josephine M McHugh, Siwo R de Kloet
openaire   +1 more source

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