Results 1 to 10 of about 3,069 (98)

IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study [PDF]

Viruses, 2023
More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany.
Bernhard Neumann, Markus Bauswein, Bernhard Banas   +2 more
exaly   +4 more sources

BoDV-1 Infection in Children and Adolescents: A Systematic Review and Meta-Analysis [PDF]

Pediatric Reports, 2023
Borna disease virus 1 (BoDV-1) can cause a severe human syndrome characterized by meningo-myeloencephalitis. The actual epidemiology of BoDV-1 remains disputed, and our study summarized prevalence data among children and adolescents (
Matteo Riccò, Silvia Ranzieri, Simona Peruzzi   +2 more
exaly   +4 more sources

Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany [PDF]

Viruses, 2023
More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region in southern Germany, we conducted the seroepidemiological BoSOT study (“BoDV-1 after solid ...
Bernhard Neumann, Benedikt M J Lampl, Markus Bauswein   +2 more
exaly   +4 more sources

First therapeutic drug monitoring of experimental favipiravir in Borna disease virus 1 (BoDV-1) encephalitis patients reveals significant gaps in antiviral treatment: a pilot investigation [PDF]

European Journal of Medical Research
Background The Borna disease virus 1 (BoDV-1) causes a rare, but severe form of encephalitis in Germany, characterized by rapid progression, late diagnosis, and a high case fatality. Therapy is experimental and recommendations are lacking.
Michael Paal, Katharina Habler, Kirsten Portner   +2 more
exaly   +3 more sources

Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses [PDF]

Emerging Microbes and Infections, 2023
Human bornavirus encephalitis is an emerging disease caused by the variegated squirrel bornavirus 1 (VSBV-1) and the Borna disease virus 1 (BoDV-1).
Mike P. Wattjes
exaly   +4 more sources

Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany [PDF]

Emerging Microbes and Infections, 2022
In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony.
Jakob Matschke, Christina Frank, Dániel Cadar   +2 more
exaly   +3 more sources

Comparative study of virus and lymphocyte distribution with clinical data suggests early high dose immunosuppression as potential key factor for the therapy of patients with BoDV-1 infection [PDF]

Emerging Microbes and Infections
Borna disease virus 1 (BoDV-1) was just recently shown to cause predominantly fatal encephalitis in humans. Despite its rarity, bornavirus encephalitis (BVE) can be considered a model disease for encephalitic infections caused by neurotropic viruses and ...
Liesche Starnecker, Tina Schaller, Mareike Schimmel   +2 more
exaly   +4 more sources

Healthcare-associated exposure to Borna disease virus 1 (BoDV-1) [PDF]

Journal of Occupational Medicine and Toxicology, 2022
The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein, Switzerland and Austria.
Judith Reinmiedl, Heiko Schulz, Viktoria C. Ruf, Moritz R. Hernandez Petzsche, Jürgen Rissland, Dennis Tappe   +5 more
doaj   +2 more sources

Calu-3 cells as novel efficient cell culture system for Borna disease virus 1 (BoDV-1) [PDF]

Virus Research
Borna disease virus 1 (BoDV-1) is the causative agent of zoonotic infections resulting in severe encephalitis with a high case-fatality rate in humans. To search for an efficient in-vitro cell culture system for the generation of BoDV-1 virus stocks, we ...
Lisa Arnold, Vanessa Schwarz, Gertrud Knoll, André Gessner, Barbara Schmidt, Markus Bauswein   +5 more
doaj   +2 more sources

Analysis of BoDV-1 status, EEG resting-state alpha activity and pro-inflammatory cytokines in adults with and without major depressive disorder [PDF]

Frontiers in Psychology
IntroductionIn severe cases, an infection with the Borna Disease Virus 1 (BoDV-1), the causative agent of Borna disease in horses, sheep, and other domestic mammals, was reported to be accompanied by cognitive dysfunctions, seizures, deep coma, or severe
Anna J. Torner, Bernhard T. Baune, Bernhard T. Baune, Bernhard T. Baune, Kristian Folta-Schoofs, Detlef E. Dietrich, Detlef E. Dietrich, Detlef E. Dietrich   +7 more
doaj   +2 more sources