BoDV-1 Infection in Children and Adolescents: A Systematic Review and Meta-Analysis [PDF]
Pediatric Reports, 2023 Borna disease virus 1 (BoDV-1) can cause a severe human syndrome characterized by meningo-myeloencephalitis. The actual epidemiology of BoDV-1 remains disputed, and our study summarized prevalence data among children and adolescents (
Federico Marchesi +2 more
exaly +9 more sources
IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study [PDF]
Viruses, 2023 More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany.
Bernhard Neumann +2 more
exaly +8 more sources
First therapeutic drug monitoring of experimental favipiravir in Borna disease virus 1 (BoDV-1) encephalitis patients reveals significant gaps in antiviral treatment: a pilot investigation [PDF]
European Journal of Medical ResearchBackground The Borna disease virus 1 (BoDV-1) causes a rare, but severe form of encephalitis in Germany, characterized by rapid progression, late diagnosis, and a high case fatality. Therapy is experimental and recommendations are lacking.
Michael Paal +2 more
exaly +7 more sources
Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany [PDF]
Viruses, 2023 More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region in southern Germany, we conducted the seroepidemiological BoSOT study (“BoDV-1 after solid ...
Bernhard Neumann +2 more
exaly +8 more sources
Comparative study of virus and lymphocyte distribution with clinical data suggests early high dose immunosuppression as potential key factor for the therapy of patients with BoDV-1 infection [PDF]
Emerging Microbes and InfectionsBorna disease virus 1 (BoDV-1) was just recently shown to cause predominantly fatal encephalitis in humans. Despite its rarity, bornavirus encephalitis (BVE) can be considered a model disease for encephalitic infections caused by neurotropic viruses and ...
Dennis Tappe +1 more
exaly +8 more sources
Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses [PDF]
Emerging Microbes and Infections, 2023 Human bornavirus encephalitis is an emerging disease caused by the variegated squirrel bornavirus 1 (VSBV-1) and the Borna disease virus 1 (BoDV-1).
Mike P Wattjes, Dennis Tappe
exaly +8 more sources
Healthcare-associated exposure to Borna disease virus 1 (BoDV-1) [PDF]
Journal of Occupational Medicine and Toxicology, 2022 The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein, Switzerland and Austria.
Judith Reinmiedl +5 more
doaj +5 more sources
Clinical Features of BoDV-1 Encephalitis: A Systematic Review
Zoonotic Diseases, 2023 Human cases of fatal encephalitis caused by Borna disease virus 1 (BoDV-1) have been increasingly reported. We envisaged the present systematic review in order to provide a comprehensive summary of clinical features associated with BoDV-1 encephalitis ...
Federico Marchesi +2 more
exaly +5 more sources
Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany [PDF]
Emerging Microbes and Infections, 2022 In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony.
Christina Frank +14 more
doaj +7 more sources
Increasing evidence of human infections by the neurotropic Borna disease virus 1 (BoDV-1) [PDF]
Virulence, 2023 Due to relatively rare instances of human infections by the Borna disease virus 1 (BoDV-1) and the difficulty of developing and validating a test for diagnosing it, human cases of fatal encephalitis caused by BoDV-1 have been difficult to confirm ...
Michaela Cain, Hinh Ly
doaj +5 more sources