Results 1 to 10 of about 311 (94)

Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany. [PDF]

Emerg Microbes Infect, 2022
In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony.
Frank C, Wickel J, Brämer D, Matschke J, Ibe R, Gazivoda C, Günther A, Hartmann C, Rehn K, Cadar D, Mayer TE, Pörtner K, Wilking H, Schmidt-Chanasit J, Tappe D.   +14 more
europepmc   +3 more sources

IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study. [PDF]

Viruses, 2023
More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany.
Eidenschink L, Knoll G, Tappe D, Offner R, Drasch T, Ehrl Y, Banas B, Banas MC, Niller HH, Gessner A, Köstler J, Lampl BMJ, Pregler M, Völkl M, Kunkel J, Neumann B, Angstwurm K, Schmidt B, Bauswein M.   +18 more
europepmc   +4 more sources

Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany. [PDF]

Viruses, 2023
More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region in southern Germany, we conducted the seroepidemiological BoSOT study (“BoDV-1 after solid ...
Bauswein M, Eidenschink L, Knoll G, Neumann B, Angstwurm K, Zoubaa S, Riemenschneider MJ, Lampl BMJ, Pregler M, Niller HH, Jantsch J, Gessner A, Eberhardt Y, Huppertz G, Schramm T, Kühn S, Koller M, Drasch T, Ehrl Y, Banas B, Offner R, Schmidt B, Banas MC.   +22 more
europepmc   +4 more sources

Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses. [PDF]

Emerg Microbes Infect, 2023
Human bornavirus encephalitis is an emerging disease caused by the variegated squirrel bornavirus 1 (VSBV-1) and the Borna disease virus 1 (BoDV-1).
Huhndorf M, Juhasz J, Wattjes MP, Schilling A, Schob S, Kaden I, Klaß G, Tappe D.   +7 more
europepmc   +4 more sources

Is vaccination a feasible public health strategy against fatal Borna disease virus 1 (BoDV-1) encephalitis? An epidemiological perspective. [PDF]

PLoS Pathog
Human Borna disease virus 1 (BoDV-1) encephalitis is characterized by rapid clinical progression, an absence of a causal therapy and an extremely high case fatality rate.
Pörtner K, Frank C, Wilking H, Stark K, Herden C, Beer M, Rubbenstroth D, Tappe D.   +7 more
europepmc   +5 more sources

First therapeutic drug monitoring of experimental favipiravir in Borna disease virus 1 (BoDV-1) encephalitis patients reveals significant gaps in antiviral treatment: a pilot investigation. [PDF]

Eur J Med Res
Background The Borna disease virus 1 (BoDV-1) causes a rare, but severe form of encephalitis in Germany, characterized by rapid progression, late diagnosis, and a high case fatality. Therapy is experimental and recommendations are lacking.
Paal M, Habler K, Ewert A, Vogeser M, Grosse L, Lieftüchter V, Tauber SC, Schiefer J, Allartz P, Tappe D, Pörtner K.   +10 more
europepmc   +3 more sources

Healthcare-associated exposure to Borna disease virus 1 (BoDV-1). [PDF]

J Occup Med Toxicol, 2022
The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein, Switzerland and Austria.
Reinmiedl J, Schulz H, Ruf VC, Hernandez Petzsche MR, Rissland J, Tappe D.   +5 more
europepmc   +2 more sources

Ribavirin Treatment for Severe Schizophrenia with Anti-Borna Disease Virus 1 Antibodies 30 Years after Onset

Case Reports in Psychiatry, 2023
Objective. Borna disease virus 1 (BoDV-1) was proven to cause fatal encephalitis in humans in 2018. However, the effects of persistent infections remain unclear.
Hidenori Matsunaga, Akio Fukumori, Kohji Mori, Takashi Morihara, Shunsuke Sato, Kyoko Kitauchi, Kanta Yanagida, Kazumi Taguchi, Tomoyuki Honda, Keizo Tomonaga   +9 more
doaj   +2 more sources

Calu-3 cells as novel efficient cell culture system for Borna disease virus 1 (BoDV-1). [PDF]

Virus Res
Borna disease virus 1 (BoDV-1) is the causative agent of zoonotic infections resulting in severe encephalitis with a high case-fatality rate in humans. To search for an efficient in-vitro cell culture system for the generation of BoDV-1 virus stocks, we ...
Arnold L, Schwarz V, Knoll G, Gessner A, Schmidt B, Bauswein M.   +5 more
europepmc   +2 more sources

Borna Disease Virus 1 as Cause of Fatal Meningoencephalomyelitis in Wild Hedgehogs, Germany, 2022-2025. [PDF]

Emerg Infect Dis
Borna disease virus 1 (BoDV-1) causes encephalitis with a fatality rate of >90% in domestic mammals and humans. Currently, the bicolored white-toothed shrew is the only known reservoir host. We report BoDV-1 infections in 15 wild European hedgehogs from
Michelakaki E, Schade B, Boehm B, Kappe E, Suchowski M, Kupca A, Schumacher M, Gager AM, Liesche-Starnecker F, Fiedler S, Schwarz E, Bago Z, Blutke A, Beer M, Rubbenstroth D, Matiasek K.   +15 more
europepmc   +2 more sources