Results 41 to 50 of about 311 (94)

Bornavirus Encephalitis Shows a Characteristic Magnetic Resonance Phenotype in Humans

open access: yesAnnals of Neurology, Volume 88, Issue 4, Page 723-735, October 2020., 2020
Objective The number of diagnosed fatal encephalitis cases in humans caused by the classical Borna disease virus (BoDV‐1) has been increasing, ever since it was proved that BoDV‐1 can cause human infections. However, awareness of this entity is low, and a specific imaging pattern has not yet been identified. We therefore provide the first comprehensive
Tom Finck   +12 more
wiley   +1 more source

Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews. [PDF]

open access: yesPLoS ONE, 2015
Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed.
Daniel Nobach   +6 more
doaj   +1 more source

Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

open access: yesiScience, 2022
Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin.
Florent Henri Marty   +8 more
doaj   +1 more source

Genome-wide profiling of long noncoding RNA expression patterns and CeRNA analysis in mouse cortical neurons infected with different strains of borna disease virus

open access: yesGenes and Diseases, 2019
Borna disease virus 1 (BoDV-1) is neurotropic prototype of Bornaviruses causing neurological diseases and maintaining persistent infection in brain cells of mammalian species.
Lin Sun   +9 more
doaj   +1 more source

Infections of horses and shrews with Bornaviruses in Upper Austria: a novel endemic area of Borna disease

open access: yesEmerging Microbes and Infections, 2017
Borna disease, a lethal infection with Borna disease virus-1 (BoDV-1), was diagnosed in four horses from Upper Austria in 2015 and 2016. All cases occurred in winter (two cases in February 2015 and two cases in December 2016), and the maximal distance of
Herbert Weissenböck   +6 more
doaj   +1 more source

Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease

open access: yesEmerging Microbes and Infections, 2022
Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case definitions, diagnostic algorithms and neuropathology have been described, very little is known about the
Jessica Rauch   +11 more
doaj   +1 more source

Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing

open access: yesViruses, 2022
Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that pose a
Nicolas Tarbouriech   +14 more
doaj   +1 more source

Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive–compulsive disorder

open access: yesBMC Psychiatry, 2022
Background Borna disease virus 1 (BoDV-1) is a non-segmented, negative-strand RNA virus that persistently infects mammals including humans. BoDV-1 worldwide occurring strains display highly conserved genomes with overlapping genetic signatures between ...
Yuanyuan Zhang   +5 more
doaj   +1 more source

Risk factors for Borna disease virus 1 encephalitis in Germany – a case–control study

open access: yesEmerging Microbes and Infections, 2023
In 2018, Borna Disease Virus 1 (BoDV-1) was confirmed as a human zoonotic pathogen causing rare but fatal encephalitis in Germany. While diagnostic procedures and the clinical picture have been described, epidemiology remains mysterious.
Kirsten Pörtner   +5 more
doaj   +1 more source

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Borna disease

open access: yesEFSA Journal, Volume 15, Issue 7, July 2017., 2017
Abstract Borna disease has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of Borna disease to be listed, Article 9 for the categorisation of Borna disease according to disease prevention and control rules as in Annex IV and Article ...
EFSA Panel on Animal Health and Welfare (AHAW)   +26 more
wiley   +1 more source

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