Results 31 to 40 of about 311 (94)

Evidence of rustrela virus-associated feline staggering disease in Sweden since the 1970s. [PDF]

Acta Vet Scand
Background Staggering disease (SD) is a severe neurological disease that has been regularly reported in Swedish cats since the beginning of the 1970s.
Thilén E, Rubbenstroth D, Tengstrand S, Pfaff F, Wensman JJ, Ley C.   +5 more
europepmc   +2 more sources

Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report

BMC Infectious Diseases, 2021
Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Arnt Ebinger, Christiane Herden, Christoph Schulze, Birgit Muntau, Petra Eggert, Petra Allartz, Gerlind Schuldt, Jonas Schmidt-Chanasit, Martin Beer, Dennis Rubbenstroth   +13 more
doaj   +1 more source

Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein

Acta Crystallographica Section F, Volume 79, Issue 3, Page 51-60, March 2023., 2023
The phosphoprotein is an essential component of the replication complex in bornaviruses. Here, using X‐ray crystallography, the structure of the phosphoprotein from Borna disease virus 1 is presented and its flexibility in solution is characterized.Bornaviruses are RNA viruses with a mammalian, reptilian, and avian host range.
Jack D. Whitehead, Jonathan M. Grimes, Jeremy R. Keown   +2 more
wiley   +1 more source

Impact of Borna Disease Virus Infection on the Transcriptome of Differentiated Neuronal Cells and Its Modulation by Antiviral Treatment

Viruses, 2023
Borna disease virus (BoDV-1) is a highly neurotropic RNA virus that causes neurobehavioral disturbances such as abnormal social activities and memory impairment.
Da Teng, Keiji Ueda, Tomoyuki Honda
doaj   +1 more source

New World camelids are sentinels for the presence of Borna disease virus

Transboundary and Emerging Diseases, Volume 69, Issue 2, Page 451-464, March 2022., 2022
Abstract Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV‐1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white‐toothed shrew (Crocidura leucodon) was identified as a persistently infected species involved in virus transmission.
Alexandra J. Malbon, Ralf Dürrwald, Jolanta Kolodziejek, Norbert Nowotny, Ralph Kobera, Dietrich Pöhle, Aemero Muluneh, Eva Dervas, Christopher Cebra, Frank Steffen, Giulia Paternoster, Christian Gerspach, Monika Hilbe   +12 more
wiley   +1 more source

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020

Emerging Infectious Diseases, 2021
Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1).
Philip Eisermann, Dennis Rubbenstroth, Daniel Cadar, Corinna Thomé-Bolduan, Petra Eggert, Alexander Schlaphof, Frank Leypoldt, Martin Stangel, Thorsten Fortwängler, Florian Hoffmann, Andreas Osterman, Sabine Zange, Hans-Helmut Niller, Klemens Angstwurm, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Martin Beer, Jonas Schmidt-Chanasit, Dennis Tappe   +19 more
doaj   +1 more source

BoDV-1 Infection in Children and Adolescents: A Systematic Review and Meta-Analysis

Pediatric Reports, 2023
Borna disease virus 1 (BoDV-1) can cause a severe human syndrome characterized by meningo-myeloencephalitis. The actual epidemiology of BoDV-1 remains disputed, and our study summarized prevalence data among children and adolescents (
Matteo Riccò, Ilaria Zanella, Elia Satta, Silvia Ranzieri, Silvia Corrado, Federico Marchesi, Simona Peruzzi   +6 more
doaj   +1 more source

A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection

Frontiers in Microbiology, 2019
Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng, Shunsuke Obika, Keiji Ueda, Tomoyuki Honda   +3 more
doaj   +1 more source

Long-term Elevation of Complement Factors in Cerebrospinal Fluid of Patients With Borna Disease Virus 1 Encephalitis. [PDF]

J Infect Dis
Bauswein M, Zoubaa S, Toelge M, Eidenschink L, Riemenschneider MJ, Neumann B, Lee DH, Eid E, Tappe D, Niller HH, Gessner A, Schmidt B, Bülow S, Angstwurm K.   +13 more
europepmc   +2 more sources

Vaccination against Borna Disease: Overview, Vaccine Virus Characterization and Investigation of Live and Inactivated Vaccines

Viruses, 2022
(1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s.
Ralf Dürrwald, Jolanta Kolodziejek, Djin-Ye Oh, Sibylle Herzog, Heinrich Liebermann, Nikolaus Osterrieder, Norbert Nowotny   +6 more
doaj   +1 more source