Results 31 to 40 of about 27,550,913 (122)

Borna Disease Virus 1 as Cause of Fatal Meningoencephalomyelitis in Wild Hedgehogs, Germany, 2022–2025 [PDF]

Emerging Infectious Diseases
Borna disease virus 1 (BoDV-1) causes encephalitis with a fatality rate of >90% in domestic mammals and humans. Currently, the bicolored white-toothed shrew is the only known reservoir host. We report BoDV-1 infections in 15 wild European hedgehogs from
Effrosyni Michelakaki, Benjamin Schade, Brigitte Boehm, Eva Kappe, Marcel Suchowski, Anne Kupca, Magdalena Schumacher, Anna Maria Gager, Friederike Liesche-Starnecker, Sonja Fiedler, Eva Schwarz, Zoltan Bago, Andreas Blutke, Martin Beer, Dennis Rubbenstroth, Kaspar Matiasek   +15 more
doaj   +2 more sources

Highly specific serological diagnosis of Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1 (VSBV-1) encephalitis by novel antibody isotype assay with multiple viral antigens.

Journal of Clinical Virology
BACKGROUND Human bornavirus encephalitis is an emerging, severe and nearly uniformly fatal zoonotic disease in Germany. The etiological pathogens so far encompass the Borna disease virus 1 (BoDV-1) and the variegated squirrel bornavirus 1 (VSBV-1). While
Mathias Schlegel, Petra Allartz, Ariane Wenzel, Thomas Faupel, Klemens Loester, D. Tappe   +5 more
semanticscholar   +3 more sources

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses [PDF]

Microbiology and Immunology, Volume 70, Issue 2, Page 80-90, February 2026.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu, Takehiro Kanda, Ryo Komorizono, Madoka Sakai, Alexander Leacy, Leonardo Susta, Akiko Makino, Keizo Tomonaga   +7 more
wiley   +2 more sources

Multimodal profiling of immune responses reveals innate-adaptive immune imbalance in human bornavirus encephalitis [PDF]

Acta Neuropathologica Communications
Human bornavirus encephalitis (BVE) is a rare, emerging and fatal zoonotic disease mainly caused by the Borna disease virus 1 (BoDV-1), a non-cytolytic RNA virus.
Nicola Jungbäck, Przemyslaw Grochowski, Daniel Hieber, Moritz Dinser, Zuzanna Mielewczyk, Thomas Pfefferkorn, Birgit Muntau, Thomas Richter, Georg Rieder, Antonios Bayas, Klaus Hirschbühl, Bruno Märkl, Patrick Adam, Dennis Tappe, Friederike Liesche-Starnecker   +14 more
doaj   +2 more sources

Humane Infektionen mit dem Borna Disease Virus (BoDV-1)

, 2018
Untersuchungen des Friedrich-Loeffler-Instituts (FLI) in Zusammenarbeit u.a. mit den Universitäts­kliniken in Regensburg, München und Leipzig identifizierten erstmals das klassische Bornavirus (Borna disease virus 1, BoDV-1; Spezies Mammalian 1 Bornavirus) als wahrscheinlichen Auslöser von schweren Entzündungen des Gehirns (Enzephalitis) beim Menschen.
Robert Koch-Institut
semanticscholar   +3 more sources

Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]

npj Viruses
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda, Pauline Dianne Santos, Dirk Höper, Martin Beer, Dennis Rubbenstroth, Keizo Tomonaga   +5 more
doaj   +2 more sources

Absence of Bornavirus RNA in Wild Canids and Mustelids in Croatia [PDF]

Microorganisms
Bornaviruses are neurotropic, negative-sense RNA viruses with zoonotic potential, notably Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1 (VSBV-1).
Andreja Jungić, Jelena Prpić, Antun Beljan, Marina Prišlin Šimac, Dinko Novosel, Šimun Naletilić, Marica Lolić, Iva Kilvain, Tibor Andreanszky, Vladimir Savić, Lorena Jemeršić, Mario Škrivanko, Ivana Lojkić   +12 more
doaj   +2 more sources

Developing a universal multi-epitope protein vaccine candidate for enhanced borna virus pandemic preparedness [PDF]

Frontiers in Immunology
IntroductionBorna disease virus 1 (BoDV-1) is an emerging zoonotic RNA virus that can cause severe acute encephalitis with high mortality. Currently, there are no effective countermeasures, and the potential risk of a future outbreak requires urgent ...
Jingjing Zhang, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang, Youfang Yang, Binyu Wang, Wanting Qiu, Helin Zhang, Yuyang Qiu, Jing Yuan, Jing Yuan, Rong Dong, Rong Dong, Rong Dong, Yan Zha, Yan Zha, Yan Zha   +16 more
doaj   +2 more sources

Impact of Borna Disease Virus Infection on the Transcriptome of Differentiated Neuronal Cells and Its Modulation by Antiviral Treatment

Viruses, 2023
Borna disease virus (BoDV-1) is a highly neurotropic RNA virus that causes neurobehavioral disturbances such as abnormal social activities and memory impairment.
Da Teng, Keiji Ueda, Tomoyuki Honda
doaj   +1 more source

Evidence of rustrela virus-associated feline staggering disease in Sweden since the 1970s [PDF]

Acta Veterinaria Scandinavica
Background Staggering disease (SD) is a severe neurological disease that has been regularly reported in Swedish cats since the beginning of the 1970s.
Emma Thilén, Dennis Rubbenstroth, Sofia Tengstrand, Florian Pfaff, Jonas Johansson Wensman, Cecilia Ley   +5 more
doaj   +2 more sources